Monday, 23 January 2017

TEST BANK OF Campbell Biology 10th Edition BY Reece

TEST BANK OF Campbell Biology 10th Edition BY Reece

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Campbell Biology, 10e (Reece)
Chapter 39   Plant Responses to Internal and External Signals

1) The detector of light during de-etiolation (greening) of a tomato plant is (are) _____.
A) carotenoids
B) xanthophylls
C) phytochrome
D) auxin




2) Plant hormones _____.
A) in plant cells naturally exist in very large amounts
B) change their shape in response to stimulus
C) are unable to move from one cell to another
D) affect only cells with the appropriate receptor




3) Which of the following can function in signal transduction in plants ?
I)   calcium ions
II)  nonrandom mutations
III)      receptor proteins
IV)      autochrome
V)  secondary messengers
A) only I, III, and IV
B) only I, II, and V
C) only I, III, and V
D) only II, III, and V




4) Plant hormones produce their effects by _____.
I)   altering the expression of genes
II)  modifying the permeability of the plasma membrane
III)      modifying the structure of the nuclear envelope membrane
A) only I
B) only II
C) only III
D) only I and II




5) Plant hormonal regulation differs from animal hormonal regulation in that _____.
A) there are no dedicated hormone-producing organs in plants as there are in animals
B) all production of hormones is local in plants with little long-distance transport
C) only animal hormone concentrations are developmentally regulated
D) only animal hormones may have either external or internal receptors




6) Which of the following plant growth responses is primarily due to the action of auxins?
A) leaf abscission
B) cell division
C) the detection of photoperiod
D) phototropism




7) Auxins in plants are known to affect which of the following processes?
I)   gravitropism of shoots
II)  maintenance of seed dormancy
III)      phototropism of shoots
IV)      inhibition of lateral buds
V)  apical dominance
A) only I and II
B) only I, III and V
C) only I, III, IV and V
D) only II, III, IV and V




8) Experiments on the positive phototropic response of plants indicate that _____.
A) light destroys auxin
B) auxin moves down the plant apoplastically
C) auxin is synthesized in the area where the stem bends
D) auxin can move to the shady side of the stem





9) Which of the following statements best summarizes the acid-growth hypothesis in an actively growing shoot?
A) Auxin stimulates proton pumps in the plasma membrane and tonoplast.
B) Auxin-activated proton pumps lower the pH of the cell wall, which breaks bonds and makes the walls more flexible.
C) Auxins and gibberellins together act as a lubricant to help stretch cellulose microfibrils.
D) Auxins activate aquaporins that increase turgor pressure in the cells.



10) Which of the following conclusions is supported by the research of both Went and Charles and Francis Darwin on shoot responses to light?
A) When shoots are exposed to light, a chemical substance migrates toward the light.
B) A chemical substance involved in shoot bending is produced in shoot tips.
C) Once shoot tips have been cut, normal growth cannot be induced.
D) Light stimulates the synthesis of a plant hormone that responds to light.




11) An eccentric millionaire botanist has offered a $25,000 scholarship to anyone who can successfully get a plant to grow through a vertical maze in complete darkness. The maze is not in a box; the maze is simply drawn on the wall, and the contestants must get their plant to grow in a pattern that matches the path through the maze. You need the money and feel confident that you can accomplish this task. Which of the following techniques will help you succeed?
A) Apply auxin directly to the shoot tip on the side to which you want the tip to bend.
B) Apply auxin directly to the part of the stem just below the tip opposite from the direction you want the stem to bend.
C) Inject compounds that block auxin receptors into the part of the stem opposite from the direction you want the stem to bend.
D) Plant the roots in two different pots, and apply auxin to the root bucket that is on the same side as the direction you want the plant to bend.




12) You have a small tree in your yard that is the height that you want it, but does not have as many branches as you want. How can you prune it to trigger it to increase the number of branches?
A) Cut off the leaves at the ends of several branches.
B) Cut off the tips of the main shoots.
C) Cut off lower branches.
D) Cut off the leaves at the base of most of the branches.




13) As cytokinins are primarily produced in roots, what route would they travel to influence lateral shoot formation in a recently topped tree?
A) symplastic
B) trachieds/vessels
C) phloem
D) apoplastic



14) Who might be interested in using cytokinins?
A) grocers, to spray on fruit to enhance ripening in the store
B) consumers, to spray on fruit before eating to enhance taste
C) florists, to dip stems in to keep leaves green longer
D) farmers, to spray on fruit after picking to stall ripening




15) If a farmer wanted more loosely packed clusters of grapes, he would most likely spray the immature bunches with _____.
A) auxin
B) gibberellins
C) cytokinins
D) abscisic acid




16) A researcher found a beautiful plant while traveling in Alaska and collected its seeds. When she came back to Florida, she soaked some seeds in pure water and some in water with a hormone. When she put the seeds in soil to grow, only the seeds that had been soaked with the hormone germinated. The hormone most likely was _____.
A) gibberellin
B) abscisic acid (ABA)
C) auxin
D) ethylene





17) _____ prevents seeds from germinating until conditions are favorable for the growth of the plant.
A) Ethylene
B) Zeaxanthin
C) Gibberellin
D) Abscisic acid



18) A population of plants experiences several years of severe drought. Much of the population dies due to lack of water, but a few individuals survive. You set out to discover the physiological basis for their adaptation to such an extreme environmental change. You hypothesize that the survivors have the ability to synthesize higher levels of _____ than their siblings do.
A) auxin
B) gibberellin
C) cytokinin
D) abscisic acid




19) If you were shipping green bananas to a supermarket thousands of miles away, which of the following chemicals would you want to eliminate from the plants' environment?
A) carbon dioxide
B) cytokinins
C) ethylene
D) auxin




20) In the fall, the leaves of some trees change color. This happens because chlorophyll breaks down and the accessory pigments become visible. What hormone is responsible for this?
A) phototropin
B) abscisic acid
C) cytokinin
D) ethylene





21) Which type of mutant would be most likely to produce a bushier phenotype?
A) auxin overproducer
B) strigolactone overproducer
C) cytokinin underproducer
D) strigolactone underproducer




22) Plant growth regulators _____.
A) only act by altering gene expression
B) often have a multiplicity of effects
C) function independently of other hormones
D) affect the division and elongation, but not the differentiation, of cells



23) Vines in tropical rain forests must grow toward large trees before being able to grow toward the sun. To reach a large tree, the most useful kind of growth movement for a tropical vine presumably would be _____.
A) negative thigmotropism
B) negative phototropism
C) negative gravitropism
D) the opposite of circadian rhythms




24) In lettuce seeds, blue light initiates germination. If you measured hormone levels within the seed, which hormone would be produced upon exposure to blue light?
A) gibberellin
B) ethylene
C) abscisic acid
D) cytokinins





25) Upon exposure to blue light, plants not only begin to grow toward the light, but move their chloroplasts to the sunny side of each cell. The adaptive advantage of moving chloroplasts to the sunny side of each cell _____.
A) maximizes light absorption by the chloroplasts for photosynthesis
B) increases production of phototropic hormones
C) maximizes heat absorption by the chloroplasts for cellular respiration
D) increases adenosine triphosphate (ATP) production during the light-independent reactions




26) Mammalian eyes sense light because the photoreceptor cells have molecules called opsins, which change structure when exposed to light. Which of the following plant molecules would be analogous to mammalian opsins in their light-sensing ability?
A) auxin and phytochrome
B) auxin and Pfr
C) Pfr and phytochrome
D) cytokinins and phototropins



27) Seed packets give a recommended planting depth for the enclosed seeds. The most likely reason some seeds are to be covered with only -inch of soil is that the _____.
A) seedlings do not have an etiolation response
B) seeds require light to germinate
C) seeds require a higher temperature to germinate
D) seeds are very sensitive to waterlogging




28) Suppose a plant had a photosynthetic pigment that absorbed far-red wavelengths of light. In which of the following environments could that plant thrive?
A) on the surface of a lake
B) on the forest floor, beneath a canopy of taller plants
C) on the ocean floor, in very deep waters
D) on mountaintops, closer to the Sun





29) The biological clock controlling circadian rhythms must ultimately _____.
A) depend on environmental cues
B) affect gene transcription
C) stabilize on a 24-hour cycle
D) speed up or slow down with increasing or decreasing temperature




30) Many plants flower in response to day-length cues. Which of the following statements best summarizes this phenomenon?
A) As a rule, short-day plants flower in the summer.
B) As a rule, long-day plants flower in the spring or fall.
C) Long-day plants flower in response to long days, not short nights.
D) Flowering in short-day and long-day plants is controlled by phytochrome.




31) Plants often use changes in day length (photoperiod) to trigger events such as dormancy and flowering. It is logical that plants have evolved this mechanism because photoperiod changes _____.
A) are more predictable than air temperature changes
B) predict moisture availability
C) are modified by soil temperature changes
D) can reset the biological clock



32) A gardener in Canada wants to surprise his mother on her birthday and make her favorite hibiscus bush flower in May instead of at the end of June. The bush is growing in the greenhouse. Which of the following might make the hibiscus bush flower early?
A) grafting leaves of a hibiscus that was exposed to long night
B) grafting leaves of a hibiscus that was exposed to short night
C) exposing flower buds of the hibiscus bush to long nights
D) exposing flower buds of the hibiscus bush to short nights





33) Which of the following can be sensed by plants?
I)   gravity
II)  pathogens
III)      wind
IV)      light
A) only I and III
B) only I, II, and IV
C) only II, III, and IV
D) I, II, III, and IV




34) You have discovered a previously unidentified plant, and you cultivate it in your lab. You notice that its flowers close when people are talking, yet are open when the lab is relatively quiet. You suspect that this plant may have the ability to hear! Which of the following hypotheses is (are) the most reasonable to explain this phenomenon?
I)   There is a cell-surface protein on the epidermal cells that becomes phosphorylated in response to vibration by sound waves.
II)  There are tiny hairs on epidermal cells that bend in response to the vibration of sound waves, triggering an action potential in epidermal cells.
III)      There is a cell-surface receptor on root cells that becomes phosphorylated when the soil vibrates in response to sound waves.
A) only I
B) only II
C) only III
D) I, II, and III




35) Shoots that grow vertically toward the sun can be characterized as _____.
A) positive for phototropism and negative for gravitropism
B) neutral for phototropism and positive for gravitropism
C) negative for phototropism and positive for gravitropism
D) positive for phototropism and neutral for gravitropism




36) Suppose you laid a seedling on its side so that the root was parallel to the ground as shown in the figure above. Several hours after the change in position, where in the root cells (position A, B, or C in the figure above) would you find the amyloplasts?
A) A
B) B
C) C




37) The rapid leaf movements resulting from a response to touch (thigmotropism) primarily involve _____.
A) potassium channels
B) nervous tissue
C) aquaporins
D) stress proteins




38) In extremely cold regions, woody species may survive freezing temperatures by _____.
A) emptying water from the vacuoles to prevent freezing
B) decreasing the numbers of phospholipids in cell membranes
C) decreasing the fluidity of all cellular membranes
D) increasing cytoplasmic levels of specific solute concentrations, such as sugars




39) Most scientists agree that global warming is underway; thus, it is important to know how plants respond to heat stress. Which of the following would be a useful line of inquiry to try and improve plant response and survival to heat stress?
A) the production of heat-stable carbohydrates
B) increased production of heat-shock proteins
C) the opening of stomata to increase evaporational heat loss
D) protoplast fusion experiments with xerophytic plants




40) When an arborist prunes a limb off a valuable tree, he or she may paint the cut surface. The primary purpose of the paint is to _____.
A) minimize water loss by evaporation from the cut surface
B) improve the appearance of the cut surface
C) stimulate growth of the cork cambium to "heal" the wound
D) block entry of pathogens through the wound




41) You are out working in your garden, and you notice that one of your favorite flowering plants has black, dead spots on the leaves. You immediately suspect that the plant has been invaded by a pathogen and has initiated a(n) _____.
A) avirulence response
B) hypersensitive response
C) resistance response
D) virulence response




42) Generalized defense responses in organs distant from the infection site are called _____.
A) hyperactive responses
B) systemic acquired resistance
C) pleiotropy
D) hyperplasia





43) A certain bacterium infects a plant's upper leaves. A few days later, bacteria of the same species attempt to infect the same plant's roots but are unsuccessful. What process is responsible for the plant's ability to prevent this infection?
A) antivirulence response
B) pathogenesis resistance
C) systemic acquired resistance
D) sequential immunity



44) A particular species of virus carries a gene for salicylate hydroxylase, an enzyme that breaks down salicylic acid. Will this virus be more or less virulent to plants than other viruses?
A) more
B) less
C) This will not make the virus more or less virulent.




45) Which event during the evolution of land plants favored the synthesis of secondary compounds?
A) the greenhouse effect throughout the Devonian period
B) the reverse-greenhouse effect during the Carboniferous period
C) the association of the roots of land plants and fungi
D) the rise of herbivory




46) The major function of the medicinal compounds in plants is to _____.
A) attract pollinators for seed dispersal
B) attract insects and birds to spread seeds and fruits
C) defend the plant against herbivores
D) defend the plant against microbes





47) For a plant to initiate chemical responses to herbivory, before it is directly affected by herbivores, _____.
A) a plant must have already flowered at least once
B) volatile "signal" compounds must be perceived
C) gene-for-gene intraspecific recognition must occur
D) phytoalexins must be released



Use the following information to answer the question(s) below.

Some plants have continually produced secondary defense compounds. Other plants are induced to form secondary defense compounds when they are injured. Corn seedling leaves that are chewed on by the caterpillars of a type of cutworm moth emit immediate volatile chemicals (LOX products), and after six hours large amounts of terpenoid compounds are released into the air. The terpenoids are released not only from the leaf being chewed, but from all leaves of the plant. The terpenoid compounds attract a parasitoid wasp female that lays her eggs on the caterpillar. When the wasp larvae hatch, they eat and kill the moth caterpillar. (T.C.J. Turlings, J. H. Loughrin, P. J. McCall, U. S. R. Rose, W. J. Lewis, and J. H. Tumlinson. 1995. How caterpillar-damaged plants protect themselves by attracting parasitic wasps. Proceedings of the National Academy of Sciences 92:4169-74.)

48) Refer to the paragraph on how caterpillar-damaged plants protect themselves by attracting parasitic wasps. What can you conclude based only on the information in the preceding paragraph?
A) The attracting terpenoid compounds are always present in the corn seedling.
B) Physical injury by the caterpillar mouthparts results in the immediate release of terpenoids.
C) Chemical signals from the caterpillar saliva attract the parasitic wasp.
D) The parasitoid wasp is attracted by compounds produced by an injured corn plant.

49) Refer to the paragraph on how caterpillar-damaged plants protect themselves by attracting parasitic wasps. To test the hypothesis that caterpillar saliva and a wound are both necessary to attract the parasitoid wasps you would need to include which of the following in your experiment?
I)   Slash the corn leaves with a razor blade.
II)  Put caterpillar saliva on a leaf wound.
III)      Put caterpillar saliva on an intact leaf.
A) only I
B) only II
C) only III
D)  I, II, and III






50) You may have observed plants rotate towards a light source, thereby increasing the plant’s ability to intercept light energy and increase photosynthesis. You, however, are given the task of preventing grass seedlings from rotating toward the light. Using your knowledge of phototropism, which of the following experimental procedures would you use to complete your task?
A) Cover the growing tip of the grass seedling with black paper.
B) Supply the seedlings with very dim light. (red light does not induce a bend)
C) Cover the portion of the seedling below the tip with a black shield.
D) Supply the seedling with nutrient-rich fertilizer solution.



51) A plant scientist was hired by a greenhouse operator to devise a way to force iris plants to bloom in the short days of winter. Iris normally blooms as long-day (short-night) plants. Which of the following has the best chance of creating iris blooms in winter?
A) Artificially increase the period of darkness in the greenhouse.
B) Increase the temperature to more closely follow summer temperatures.
C) Alternate four hours of darkness with four hours of light repeatedly over each 24-hour period.
D) Interrupt the long winter nights with a brief period of light.



52) An individual plant was discovered that could not grow towards light. After some research, it was determined that the reason was a defective gene that did not allow for the level of cell elongation necessary for a phototropic response. This mutation greatly reduces the fitness of the individual plant. Which reason best describes the reason for the loss of fitness?
A)  The plant was too short to attract insects for pollination.
B) The plant could not adjust to directional light, which reduced photosynthetic activity and therefore energy available for reproduction.
C) Because the plant grew much taller and straighter, resources that could be used for reproduction were used for growth.
D) The loss of a phototropic response meant that the plant’s seeds could not germinate so reproduction would be unsuccessful.


 Campbell Biology, 10e (Reece)
Chapter 40   Basic Principles of Animal Form and Function

1) Penguins, seals, and tuna have body forms that permit rapid swimming, because _____.
A) all share a recent common ancestor
B) all of their bodies have been compressed since birth by intensive underwater pressures
C) the shape is a convergent evolutionary solution, which reduces drag while swimming
D) this is the only shape that will allow them to maintain a constant body temperature in water




2) As the size of some animals has evolved to greater sizes, the effectiveness of their adaptations that promote exchanges with the environment have also increased. For example, in many larger organisms, evolution has favored lungs and a digestive tract with _____.
A) more branching or folds
B) increased thickness
C) larger cells
D) decreased blood supply




3) Much of the coordination of vertebrate body functions via chemical signals is accomplished by the _____.
A) respiratory system
B) endocrine system
C) integumentary system
D) excretory system




4) Compared with a smaller cell, a larger cell of the same shape has _____.
A) less surface area
B) less surface area per unit of volume
C) a smaller average distance between its mitochondria and the external source of oxygen
D) a smaller cytoplasm-to-nucleus ratio





5) If you were to view a sample of animal tissue under a light microscope and notice an extensive extracellular matrix surrounding a tissue, which tissue type would you most suspect?
A) connective
B) epithelial
C) nervous
D) striated muscle



6) Some animals have no gills when young, but then develop gills that grow larger as the animal grows larger. What is the reason for this increase in gill size?
A) The young of these animals are much more active than the adult, which leads to a higher BMR (basal metabolic rate) and, therefore, a higher need for oxygen.
B) Relative to their volume, the young have more surface area across which they can transport all the oxygen they need.
C) The young have a higher basal metabolic rate.
D) Relative to their surface area, the young have more body volume in which they can store oxygen for long periods of time.




7) Evolutionary adaptations that help diverse animals directly exchange matter between cells and the environment include _____.
A) a gastrovascular activity, a two-layered body, and a torpedo-like body shape
B) an external respiratory surface, a small body size, and a two-cell-layered body
C) a large body volume, a long, tubular body, and a set of wings
D) an unbranched internal surface, a small body size, and thick covering




8) All animals, whether large or small, have _____.
A) an external body surface that is dry
B) a basic body plan that resembles a two-layered sac
C) a body surface covered with hair to keep them warm
D) most of their cells in contact with an aqueous medium





9) Interstitial fluid is _____.
A) the internal environment inside animal cells
B) identical to the composition of blood
C) a common site of exchange between blood and body cells
D) found only in the lumen of the small intestine




10) Of the following choices, the epithelium with the shortest diffusion distance is _____.
A) simple squamous epithelium
B) simple columnar epithelium
C) pseudostratified ciliated columnar epithelium
D) stratified squamous epithelium



11) Most of the exchange surfaces of multicellular animals are lined with _____.
A) connective tissue
B) smooth muscle cells
C) neural tissue
D) epithelial tissue




12) Connective tissues typically have _____.
A) little space between the membranes of adjacent cells
B) the ability to transmit electrochemical impulses
C) the ability to shorten upon stimulation
D) relatively few cells and a large amount of extracellular matrix




13) If you gently bend your ear, and then let go, the shape of your ear will return because the cartilage of your ear contains_____.
A) collagenous fibers
B) elastic fibers
C) reticular fibers
D) adipose tissue





14) Blood is best classified as connective tissue because _____.
A) its cells are separated from each other by an extracellular matrix
B) it contains more than one type of cell
C) its cells can move from place to place
D) it is found within all the organs of the body




15) Most types of communication between cells utilize _____.
A) the exchange of cytosol between the cells
B) the movement of the cells
C) chemical or electrical signals
D) the exchange of DNA between the cells



16) All types of muscle tissue have _____.
A) striated banding patterns seen under the microscope
B) cells that lengthen when appropriately stimulated
C) a response that can be consciously controlled
D) interactions between actin and myosin




17) Cardiac muscle cells are both _____.
A) striated and interconnected by intercalated disks
B) smooth and under voluntary control
C) striated and under voluntary control
D) smooth and under involuntary control




18) The type of muscle tissue surrounding the intestines and blood vessels is _____.
A) skeletal muscle
B) cardiac muscle
C) intercalated cells
D) smooth muscle





19) Food moves along the digestive tract as the result of contractions by _____.
A) cardiac muscle
B) smooth muscle
C) striated muscle
D) skeletal muscle




20) The cells lining the air sacs in the lungs make up a _____.
A) simple squamous epithelium
B) stratified squamous epithelium
C) pseudostratified ciliated columnar epithelium
D) simple columnar epithelium



21) The body tissue that consists largely of material located outside of cells is _____.
A) epithelial tissue
B) connective tissue
C) skeletal muscle
D) nervous tissue




22) You are looking through a microscope at a slide of animal tissue and see a single layer of flat, closely packed cells that cover a surface. This specific tissue is most likely _____.
A) adipose
B) a tendon
C) epithelial
D) a neuron


23) Environmental influences appear to contribute to cellular mutations that lead to tumor growth. For example, certain diets lead to higher incidence of colon cancers, and overexposure to sunlight leads to higher incidence of skin cancers. The tissues in closest contact with a carcinogen or mutagen (anything that causes genetic mutations) are obviously the ones most likely to develop tumors. Carcinomas and melanomas account for well over half of all cancers. What type of tissue would you guess the term carcinoma and melanoma is most closely associated with?
A) connective
B) muscle
C) epithelial
D) nervous




24) Which of the following is a true statement about body size and physiology?
A) The amount of food and oxygen an animal requires and the amount of heat and waste it produces are inversely proportional to its mass.
B) The rate at which an animal uses nutrients and produces waste products is independent of its volume.
C) Small and large animals face different physiological challenges because an animal's body mass increases cubically while its surface area increases as a squared function.
D) The wastes produced by an animal double as its volume doubles and triple as its surface area triples.



25) An elephant and a mouse are running in full sunlight, and both overheat by the same amount above their normal body temperatures. When they move into the shade and rest, which animal will cool down faster?
A) The elephant will because it has the higher surface-area-to-volume ratio.
B) The elephant will because it has the lower surface-area-to-volume ratio.
C) The mouse will because it has the higher surface-area-to-volume ratio.
D) They will cool at the same rate because they overheated by the same amount.



26) You have a cube of modeling clay in your hands. Which of the following changes to the shape of this cube of clay will decrease its surface area relative to its volume?
A) Pinch the edges of the cube into small folds.
B) Flatten the cube into a pancake shape.
C) Round the clay up into a sphere.
D) Stretch the cube into a long, shoebox shape.




27) If an organism was discovered that had no epithelial tissues, it would require adaptations to maintain homeostasis in which of the following areas? The organism would require adaptations _____.
A) in its skeleton for structure
B) in its nervous system for sensing external stimuli
C) that would prevent water loss from the body in a terrestrial environment
D) in its muscular system for movement





The crucian carp (Carassius carassius) is a Northern European freshwater fish often inhabiting ponds that become hypoxic (have reduced oxygen levels) and even anoxic (have no oxygen) when the surface freezes during the winter. Surprisingly, when oxygen levels are normal, these fish lack the lamellae that provide a large surface area for gas exchange between water and blood: their gills are smooth. Yet when the level of oxygen in the water falls, the gill morphology undergoes a change: packing cells stop dividing and programmed cell death is induced, exposing gill lamellae that were buried in other tissue. With lamellae exposed, the gills have increased surface area for gas exchange. These changes in gill lamellar profile are reversible: investigators observed that the gills return to their normal structure within seven days after returning the fish to well-oxygenated water. (Jørund Sollid, Paula De Angelis, Kristian Gundersen, and Göran E. Nilsson. 2003. Hypoxia induces adaptive and reversible gross morphological changes in crucian carp gills. Journal of Experimental Biology 206:3667-73.)

28) Refer to the paragraph on crucian carp. Gills serve multiple functions in fish in addition to gas exchange. Given the large surface area of gills with lamellae, what is the most likely explanation for why crucian carp cover protruding lamellae in their gills when levels of oxygen are normal?
A) to prevent loss of heat to the surrounding water
B) to prevent loss of ions to the surrounding water
C) to prevent protein loss to the surrounding water
D) to prevent loss of oxygen to the surrounding water


29) Once labor begins in childbirth, contractions increase in intensity and frequency, causing more contractions to occur until delivery. The increasing labor contractions of childbirth are an example of which type of regulation?
A) positive feedback
B) negative feedback
C) feedback inhibition
D) enzymatic catalysis




30) When the body's blood glucose level rises, the pancreas secretes insulin and, as a result, the blood glucose level declines. When the blood glucose level is low, the pancreas secretes glucagon and, as a result, the blood glucose level rises. Such regulation of the blood glucose level is the result of _____.
A) catalytic feedback
B) positive feedback
C) negative feedback
D) protein-protein interactions




31) The body's automatic tendency to maintain a constant and optimal internal environment is termed _____.
A) balanced equilibrium
B) physiological chance
C) homeostasis
D) static equilibrium




32) An example of a properly functioning homeostatic control system is seen when _____.
A) the core body temperature of a runner rises gradually from 37°C to 45°C
B) the kidneys excrete salt into the urine when dietary salt levels rise
C) a blood cell shrinks when placed in a solution of salt and water
D) the blood pressure increases in response to an increase in blood volume

33) Positive feedback differs from negative feedback in that _____.
A) positive feedback benefits the organism, whereas negative feedback is detrimental
B) the positive feedback's effector responses are in the same direction as the initiating stimulus rather than opposite of it
C) the effector's response increases some parameter (such as body temperature), whereas in negative feedback it can only decrease the parameter
D) positive feedback systems have only effectors, whereas negative feedback systems have only receptors




34) Which of the following is an example of negative feedback?
A) During birthing contractions, oxytocin (a hormone) is released and acts to stimulate further contractions.
B) When a baby is nursing, suckling leads to the production of more milk and a subsequent increase in the secretion of prolactin (a hormone that stimulates lactation).
C) After a blood vessel is damaged, signals are released by the damaged tissues that activate platelets in the blood. These activated platelets release chemicals that activate more platelets.
D) When the level of glucose in the blood increases, the pancreas produces and releases the hormone insulin. Insulin acts to decrease blood glucose. As blood glucose decreases, the rate of production and release of insulin decreases as blood glucose decreases.



35) You discover a new species of bacteria that grows in aquatic environments with high salt levels. While studying these bacteria, you note that their internal environment is similar to the salt concentrations in their surroundings. You also discover that the internal salt concentrations of the bacteria change as the salt concentration in their environment changes. The new species can tolerate small changes in this way, but dies from large changes because it has no mechanism for altering its own internal salt levels. What type of homeostatic mechanism is this species using to regulate its internal salt levels?
A) conformation
B) regulation
C) integration
D) assimilation


36) Chum salmon (Oncorhynchus keta) are born in freshwater environments and then migrate to the sea. Near the end of their lives, they return to the freshwater stream where they were born to spawn. In freshwater, water constantly diffuses into the body and ions are lost from the body. In salt water, body water diffuses out of the body and excess ions are gained from the water. A salmon's gills have special cells to pump salt in or out of the body to maintain homeostasis. In response to the salmon's moves between freshwater and salt water, some cells in the gills are produced and others are destroyed. These changes made in the cells of the gills during the lifetime of an individual salmon are an example of which of the following?
A) evolution
B) trade-off
C) acclimatization
D) adaptation




37) To prepare flight muscles for use on a cool morning, hawkmoths _____.
A) relax the muscles completely until after they launch themselves into the air
B) decrease their standard metabolic rate
C) rapidly contract and relax these muscles to generate metabolic warmth
D) reduce the metabolic rate of the muscles to rest them before flight




38) In a cool environment, an ectotherm is more likely to survive an extended period of food deprivation than would an equally sized endotherm because the ectotherm _____.
A) maintains a higher basal metabolic rate
B) expends more energy per kilogram of body mass than does the endotherm
C) invests little energy in temperature regulation
D) has greater insulation on its body surface



39) Sweating allows a person to lose heat through the process of _____.
A) conduction
B) convection
C) radiation
D) evaporation


40) An example of an ectothermic organism that has few or no behavioral options when it comes to its ability to adjust its body temperature is a _____.
A) sea star living deep in the ocean
B) bass living in a farm pond
C) hummingbird flying through a prairie
D) honeybee in a hive on a rural farm




41) The panting responses that are observed in overheated birds and mammals dissipate excess heat by _____.
A) countercurrent exchange
B) acclimation
C) vasoconstriction
D) evaporation




42) Most land-dwelling invertebrates and all of the amphibians _____.
A) are ectothermic organisms with variable body temperatures
B) alter their metabolic rates to maintain a constant body temperature of 37°C
C) are endotherms but become thermoconformers when they are in water
D) become more active when environmental temperatures drop below 15°C




43) The temperature-regulating center of vertebrate animals is located in the _____.
A) thyroid gland
B) hypothalamus
C) subcutaneous layer of the skin
D) liver



44) The metabolic breakdown of specialized brown fat depots in certain animals is substantially increased during _____.
A) acclimatization
B) torpor
C) nonshivering thermogenesis
D) shivering thermogenesis




45) A moth preparing for flight on a cold morning may warm its flight muscles via _____.
A) acclimatization
B) torpor
C) evaporative cooling
D) shivering thermogenesis





46) The thin horizontal arrows in the figure above show that the _____.
A) warmer arterial blood can bypass the legs as needed, when the legs are too cold to function well
B) warmer venous blood transfers heat to the cooler arterial blood
C) warmer arterial blood transfers heat to the cooler venous blood
D) arterial blood is always cooler in the abdomen, compared to the temperature of the venous blood in the feet of the goose


47) Examine the figure above. Near a goose's abdomen, the countercurrent arrangement of the arterial and venous blood vessels causes the _____.
A) temperature difference between the contents of the two sets of vessels to be minimized
B) venous blood to be as cold near the abdomen as it is near the feet
C) blood in the feet to be as warm as the blood in the abdomen
D) loss of the maximum possible amount of heat to the environment






48) Which of the following would increase the rate of heat exchange between an animal and its environment?
A) feathers or fur
B) vasoconstriction
C) wind blowing across the body surface
D) blubber or fat layer




49) You are studying a large tropical reptile that has a high and relatively stable body temperature. How would you determine whether this animal is an endotherm or an ectotherm?
A) You know from its high and stable body temperature that it must be an endotherm.
B) You know that it is an ectotherm because it is not a bird or mammal.
C) You subject this reptile to various temperatures in the lab and find that its body temperature and metabolic rate change with the ambient temperature. You conclude that it is an ectotherm.
D) You note that its environment has a high and stable temperature. Because its body temperature matches the environmental temperature, you conclude that it is an ectotherm.




50) A woman standing and watching the stars on a cool, calm night will lose most of her body heat by _____.
A) radiation
B) convection
C) conduction
D) evaporation


51) There are advantages and disadvantages to adaptations. Animals that are endothermic are likely to be at the greatest disadvantage in _____.
A) very cold environments
B) very hot environments
C) environments with a constant food source
D) environments with variable and limited food sources



52) Which principle of heat exchange is the most important explanation for why birds look larger in colder weather because they fluff their feathers?
A) Fluffing feathers results in less cooling by radiation because feathers emit less infrared radiation than other tissues do.
B) Fluffing decreases the amount of heat lost by conduction when the bird makes contact with cold objects in its environment.
C) Fluffing creates a pocket of air near the bird that acts as insulation.
D) Fluffing decreases the surface-area-to-volume ratio, thus decreasing the amount of heat lost to the environment.




53) Snake behavior in Wisconsin changes throughout the year. For example, a snake is _____.
A) less active in winter because the food supply is decreased
B) less active in winter because it does not need to avoid predators
C) more active in summer because that is the period for mating
D) more active in summer because it can gain body heat by conduction




54) Standard metabolic rate (SMR) and basal metabolic rate (BMR) are _____.
A) used differently: SMR is measured during exercise, whereas BMR is measured at rest
B) used to compare metabolic rates during feeding and other active conditions
C) both measured across a wide range of temperatures for a given species
D) both measured in animals in a resting and fasting state


55) Independent of whether an organism is an endotherm or ectoderm, the LEAST reliable indicator of an animal's metabolic rate is the amount of _____.
A) food eaten in one day
B) heat generated in one day
C) oxygen used in mitochondria in one day
D) water consumed in one day



56) Consider the energy budgets for a human, an elephant, a penguin, a mouse, and a snake. The _____ would have the highest total annual energy expenditure, and the _____ would have the highest energy expenditure per unit mass.
A) elephant; mouse
B) elephant; human
C) human; penguin
D) mouse; snake




57) An animal's inputs of energy and materials would exceed its outputs if _____.
A) the animal is an endotherm, which must always take in more energy because of its high metabolic rate
B) it is actively foraging for food
C) it is hibernating
D) it is growing and increasing its mass




58) Which of the following animals most likely uses the largest percentage of its energy budget for homeostatic regulation?
A) a marine jelly (an invertebrate) living deep in the ocean
B) a snake in a tropical forest
C) a shark swimming in the open ocean
D) a bird living year round in a desert


59) A researcher is setting up an experiment to measure basal metabolic rate in prairie voles (Microtus ochrogaster–a small rodent). Which of the following would be the best set of conditions for the voles immediately before and during the measurement?
A) House the animals in a cage with plenty of food and water to avoid stress; conduct measurements in a warmer room than the room where housed.
B) House the animals in a cage with plenty of food and water to avoid stress; conduct measurements in a room the same temperature as the room where housed.
C) House the animals in a cage with no food for a few hours before measurement; conduct measurements in a colder room than the room where housed, and exercise the voles.
D) House the animals in a cage with no food for a few hours before measurement; conduct measurements in a room the same temperature as the room where housed.



60) Hummingbirds are small birds that require a regular food supply. When hummingbirds are faced with a situation that decreases their food supply, such as a storm, which of the following adaptations would be most useful for the bird to survive such an unpredictable and short-term absence of food resources?
A) shivering
B) torpor
C) hibernation
D) burrowing into soil




61) Organisms maintain dynamic homeostasis (internal balance) through behavioral and physiological mechanisms. Which of the following statements is an accurate explanation of a negative feedback mechanism used by animals to regulate body temperature?
A) Squirrels are able to cool themselves during warmer months by producing more brown fat, which contains abundant mitochondria and a rich blood supply.
B) Desert jackrabbits  have unusually large ears that serve as solar heat collectors to enable them to maintain their body temperatures.
C) A ground squirrel’s hypothalamus detects changes in environmental temperatures and responds by activating or suppressing metabolic heat production.
D) A goldfish slows its movements when the water temperature is lower.

Campbell Biology, 10e (Reece)
Chapter 41   Animal Nutrition

1) The following table shows the contents of a multivitamin supplement and its percentage of recommended daily values (%DV).

Dietary Supplement
% DV
Vitamin A 
  70
Vitamin C 
100
Vitamin D 
100
Vitamin E 
150
Vitamin K 
  13
Vitamin B1 
100
Vitamin B2 
100
Folic acid 
100
Vitamin B12 
    41.7
Calcium 
 20
Phosphorus 
  5
Iodine  
100
Magnesium 
  25
Zinc  
100
Copper 
100
Chromium 
125
Molybdenum 
100
Iron  
   0

The most likely reason that some of the vitamins and minerals in this supplement are found at less than 100% is that _____.
A) it would be chemically impossible to add more
B) these vitamins and minerals are too large in size to reach 100%
C) it is too easy to overdose on minerals such as phosphorus and calcium
D) it is dangerous to overdose on fat-soluble vitamins such as A and K




2) In a well-fed human eating a Western diet, the richest source of stored chemical energy in the body is _____.
A) fat in adipose tissue
B) glucose in the blood
C) protein in muscle cells
D) glycogen in muscle cells



3) Animals that migrate great distances would obtain the greatest energetic benefit of storing chemical energy as _____.
A) proteins
B) minerals
C) carbohydrates
D) fats




4) Certain nutrients are considered "essential" in the diets of some animals because _____.
A) only those animals use those nutrients
B) these animals are not able to synthesize these nutrients
C) the nutrients are necessary coenzymes
D) only certain foods contain them




5) Which pair correctly associates a physiological process with the appropriate vitamin?
A) blood clotting — vitamin C
B) normal vision — vitamin A
C) synthesis of cell membranes — vitamin D
D) production of white blood cells — vitamin K




6) Folic acid supplements have become especially important for pregnant women because _____.
A) folic acid supplies vitamins that only pregnant women can use
B) the fetus makes high levels of folic acid
C) folic acid deprivation is associated with neural tube abnormalities in a fetus
D) folic acid deprivation is a cause of heart abnormalities in a newborn




7) What is the importance of consuming an adequate amount of proteins in the diet?
A) They are most commonly used to meet energy demands of cells.
B) Proteins serve a variety of functions, and the body does not store excess quantities of protein.
C) They are used as cofactors for metabolic reactions and are required in minute quantities.
D) Proteins are necessary to produce urea and other important metabolites.



8) Three groups of cyclists consumed three different types of diets: high-carbohydrate; a diet mixed in carbohydrates, fat, and protein; or a diet higher in protein and fat. The average time each group could spend cycling over a six-hour period is shown in the above graph. What conclusion from the data would help an athlete or trainer improve performance?
A) Endurance is entirely related to diet.
B) Maintaining elevated blood sugar improves performance.
C) An early 50 percent drop in blood glucose is associated with improved endurance.
D) Diet is not at all related to endurance.




9) Which of the following animals is correctly paired with its feeding mechanism?
A) baleen whale — fluid feeder
B) aphid — suspension feeder
C) clam — substrate feeder
D) snake — bulk feeder




10) The process of obtaining food is known as _____ and requires specialized mouthparts.
A) ingestion
B) digestion
C) absorption
D) excretion



11) In marine sponges, intracellular digestion of peptides is usually immediately preceded by _____.
A) hydrolysis
B) phagocytosis
C) absorption
D) secretion




12) An advantage of a complete digestive system over a gastrovascular cavity is that the complete system _____.
A) excludes the need for extracellular digestion
B) allows for specialized regions with specialized functions
C) allows extensive branching
D) facilitates intracellular digestion




13) Because the foods eaten by animals are often composed largely of macromolecules, animals need to have mechanisms for _____.
A) dehydration synthesis
B) enzymatic hydrolysis
C) regurgitation
D) demineralization




14) Fat digestion yields fatty acids and glycerol, whereas protein digestion yields amino acids; both digestive processes _____.
A) are catalyzed by the same enzyme
B) use water molecules when breaking bonds (hydrolysis)
C) require the presence of hydrochloric acid to lower the pH
D) require adenosine triphosphate (ATP) as an energy source





15) Ingested dietary substances must cross cell membranes to be used by the body. This process is known as _____.
A) ingestion
B) digestion
C) hydrolysis
D) absorption



16) The function of mechanical digestion is to break down large chunks of food into smaller pieces. Why is this important? Smaller pieces of food _____.
A) do not taste as good as larger pieces of food
B) have more surface area for chemical digestion than do larger pieces of food
C) are easier to excrete than are larger pieces of food
D) are more easily stored in the stomach than are larger pieces of food




17) The large surface area in the gut directly facilitates _____.
A) secretion
B) absorption
C) filtration
D) temperature regulation




18) In the digestive system, peristalsis is _____.
A) a process of fat emulsification in the small intestine
B) voluntary control of the rectal sphincters regulating defecation
C) the transport of nutrients to the liver through the hepatic portal vessel
D) smooth muscle contractions that move food along the esophagus




19) Among mammals, it is generally true that _____.
A) all types of foods begin their enzymatic digestion in the mouth
B) after leaving the oral cavity, the bolus enters the larynx
C) the epiglottis prevents swallowed food from entering the trachea
D) the trachea leads to the esophagus and then to the stomach




20) Examine the digestive system structures in the figure above. The agents that help emulsify fats are produced in location _____.
A) 1
B) 3
C) 8
D) 9




21) Examine the digestive system structures in the figure above. The highest rate of nutrient absorption occurs at location_____.
A) 1
B) 4
C) 5
D) 8




22) Examine the digestive system structures in the figure above. Most of the digestion of fats occurs in structure(s) _____.
A) 3 only
B) 4 only
C) 1 and 4
D) 3 and 4




23) Examine the digestive system structures in the figure above. Bacteria that produce vitamins are found in the greatest concentration in location _____.
A) 3
B) 4
C) 5
D) 8




24) The mammalian trachea and esophagus both connect to the _____.
A) stomach
B) pharynx
C) rectum
D) epiglottis




25) Which of the following organs is correctly paired with its function?
A) stomach — protein digestion
B) large intestine — bile production
C) small intestine — starch digestion
D) pancreas — starch digestion




26) Stomach cells are moderately well adapted to the acidity and protein-digesting activities in the stomach by having _____.
A) a sufficient colony of H. pylori
B) a thick, mucous secretion and active mitosis of epithelial cells
C) a high level of secretion of enzymes by chief cells
D) a cell wall impermeable to acid




27) Villi and microvilli in the small intestine _____.
A) neutralize stomach acid
B) activate trypsinogen
C) increase the surface area to increase the efficiency of nutrient absorption
D) emulsify lipid molecules




28) Upon activation by stomach acidity, the secretions of the parietal cells _____.
A) initiate the chemical digestion of protein in the stomach
B) initiate the mechanical digestion of lipids in the stomach
C) initiate the chemical digestion of lipids in the stomach
D) delay digestion until the food arrives in the small intestine




29) Historically inaccurate diagnosis of acid reflux disorders and gastric ulcers has been improved by _____.
A) pH monitoring
B) X-ray technology
C) screening for H. pylori infections
D) sonography




30) What is the importance of the mucins that are released by salivary glands?
A) They aid in degradation of triglycerides to fatty acids and monoglycerides.
B) They are beginning the process of starch digestion.
C) They are hormonal molecules that stimulate the release of gastric juice by the stomach in anticipation of receipt of the contents of the mouth.
D) They are glycoproteins that make food slippery enough to slide easily through the esophagus.




31) Jahasz-Pocsine and co-workers found a correlation between gastric bypass surgery and neurological complications. Surgeons performed gastric bypass surgery on 150 patients at the University of Arkansas for Medical Sciences Neurology Clinic. Of the 150 patients, 26 experienced neurological complications related to the surgery. What is the most likely cause for the neurological complications?
A) sudden weight loss and caloric deficiency interfering with neurological function
B) nutrient (for example, vitamin and mineral) deficiencies
C) sloppy surgical technique of physicians performing the bypass surgery
D) infections following surgical intervention




32) Why did scientists originally hypothesize that proteolytic enzymes such as pepsin and trypsin are secreted in inactive form?
A) These proteolytic enzymes, in active form, would digest the very tissues that synthesize them.
B) They identified the hormone that activates pepsin and trypsin.
C) The stomach is too acidic to maintain these enzymes in their active form.
D) Pepsin and trypsin have never been isolated in their fully activated form.




33) Over-the-counter medications for acid reflux or heartburn block the production of stomach acid. Which of the following cells are directly affected by this medication?
A) goblet cells
B) chief cells
C) parietal cells
D) smooth muscle cells




34) Helicobacter pylori is a bacterial organism that causes ulcers and digestive disturbances. How might they survive the acid pH of the stomach?
A) They secrete buffers to neutralize acid.
B) They burrow under the mucus layer that covers the stomach epithelium.
C) They take over the parietal cells.
D) They release chemicals that decrease acid production in the stomach.

Bloom's Taxonomy:  Synthesis/Evaluation


35) The active ingredient orlistat acts to decrease the amount of fat that is absorbed by attaching to enzymes that digest fat. Which of the following are potential targets of orlistat?
A) salivary amylase
B) pepsidase
C) pancreatic lipase
D) secretin




36) The pancreas is involved in the digestion of _____.
I)   protein
II) fat
III)      nucleic acids
IV)      carbohydrates
A) I and III
B) I, II, and IV
C) II, III, and IV
D) I, II, III, and IV




37) Digestive secretions with a pH of 2 are characteristic of the _____.
A) small intestine
B) stomach
C) pancreas
D) liver




38) The bile salts _____.
A) are enzymes
B) are manufactured by the pancreas
C) emulsify fats in the duodenum
D) are normally an ingredient of gastric juice




39) The absorption of fats differs from that of carbohydrates in that _____.
A) fat absorption primarily occurs in the stomach, whereas carbohydrates are absorbed from the small intestine
B) carbohydrates need to be emulsified before they can be digested, whereas fats do not
C) most absorbed fat first enters the lymphatic system, whereas carbohydrates directly enter the blood
D) fats, but not carbohydrates, are digested by bacteria before absorption





40) Constipation can result from the consumption of a substance that _____.
A) promotes water reabsorption in the large intestine
B) speeds up movement of material in the large intestine
C) decreases water reabsorption in the small intestine
D) stimulates peristalsis



41) A significant contribution of intestinal bacteria to human nutrition is the benefit of bacterial _____.
A) production of vitamins A and C
B) absorption of organic materials
C) production of vitamin K
D) recovery of water from fecal matter




42) After surgical removal of an infected gallbladder, a person must be especially careful to restrict dietary intake of _____.
A) protein
B) sugar
C) fat
D) water




43) When a woman has her gallbladder removed, she should probably reduce her consumption of _____.
A) proteins
B) carbohydrates
C) fats
D) proteins and carbohydrates




44) If you place a small piece of a cracker on your tongue, what would you expect to happen?
A) The vitamins in the cracker are immediately absorbed.
B) Salivary amylase degrades the starch from the cracker into glucose.
C) The proteins in the cracker begin to be digested.
D) The flavor becomes less noticeable because the sugars are digested.




45) A relatively long cecum is characteristic of animals that are_____.
A) carnivores
B) herbivores
C) autotrophs
D) omnivores



46) Cattle are able to survive on a diet consisting almost entirely of plant material because cattle _____.
A) are autotrophic
B) re-ingest their feces
C) manufacture all fifteen amino acids out of sugars in the liver
D) have cellulose-digesting, symbiotic microorganisms in chambers of their stomachs




47) A zoologist analyzes the jawbones of an extinct mammal and concludes that it was an herbivore. The zoologist most likely came to this conclusion based upon _____.
A) the position of muscle attachment sites
B) the shape of the teeth
C) the size of the mouth opening
D) the angle of the teeth in the mouth




48) An enlarged cecum is typical of _____.
A) rabbits, horses, and herbivorous bears
B) carnivorous animals
C) tubeworms that digest via symbionts
D) humans and other primates




49) Coprophagy is important for the nutritional balance of _____.
A) ruminants such as cows
B) insects and arthropods
C) rabbits and their relatives
D) squirrels and some rodents





50) If you found a vertebrate skull in the woods and the teeth were sharp and scissor-like, what type of food would you expect this animal to eat?
A) grass
B) flesh of another animal
C) nectar
D) blood



51) You are most likely to observe coprophagy in _____.
A) carnivores
B) herbivores
C) fluid feeders
D) suspension feeders




52) Obesity in humans is most clearly linked to _____.
A) type 1 diabetes and prostate cancer
B) type 2 diabetes and muscle hypertrophy
C) type 2 diabetes and cardiovascular disease
D) type 2 diabetes and decreased appetite




53) If you were to jog one kilometer a few hours after lunch, which stored fuel would you probably tap?
A) muscle proteins
B) liver glycogen and muscle glycogen
C) fat stored in adipose tissue
D) blood proteins





54) Food being digested in the stomach is in a highly acidic environment. When the food is released from the stomach into the small intestine, why is the environment no longer acidic?
A) Secretin increases the flow of bicarbonate ions from the pancreas into the small intestine to neutralize the stomach acid.
B) Enterokinase activates trypsinogen, thus neutralizing the stomach acid.
C) Bile salts from the gallbladder neutralize the stomach acid.
D) When pepsinogen activates pepsin, one result is the neutralization of stomach acid in the stomach.



55) The Pimas are a group of people living in the southwestern United States and Mexico. Although Pima Indians living in the United States and Mexico have a similar genetic background, a five-fold increase in the incidence of type II diabetes mellitus among U.S. Pima has been reported. The body mass index of Mexicans of non-Pima descent, Mexicans of Pima descent, and Pimas living in the United States is shown in the figure above. Based on this information and the graph above, what can you infer about the incidence of type II diabetes mellitus?
A) Obesity is a risk factor for development of type II diabetes mellitus.
B) If you maintain a normal body weight (body mass index less than 25), you will not get type II diabetes mellitus.
C) The incidence of type II diabetes mellitus has increased in the past ten years.
D) People who develop type II diabetes mellitus are typically diagnosed in childhood or adolescence.




56) In a healthy person, after a large meal, the production of _____ will increase. After fasting, the production of _____ will increase.
A) trypsin; trypsinogen
B) glucagon; glucose
C) glucagon; pepsinogen
D) insulin; glucagon



57) If there is a strong genetic link for type II diabetes mellitus in your family, how might you minimize your risk of developing the disorder?
A) monitor your blood glucose levels daily
B) take oral insulin daily
C) maintain a healthy weight, eat a balanced direct, and exercise
D) eat complex carbohydrates like starch instead of sweets




58) When the digestion and absorption of organic carbohydrates results in more energy-rich molecules than are immediately required by an animal, the excess is _____.
A) eliminated in the feces
B) stored as starch in the liver
C) stored as glycogen in the liver and muscles
D) oxidized and converted to ATP




59) A fasting animal whose energy needs exceed those provided in its diet draws on its stored resources in which order?
A) fat, then glycogen, then protein
B) glycogen, then protein, then fat
C) liver glycogen, then muscle glycogen, then fat
D) muscle glycogen, then fat, then liver glycogen


 Campbell Biology, 10e (Reece)
Chapter 42   Circulation and Gas Exchange

1) The circulatory systems of bony fishes, rays, and sharks are most similar to _____.
A) those of birds, with a four-chambered heart
B) the portal systems of mammals, where two capillary beds occur sequentially, without passage of blood through a pumping chamber
C) those of sponges, where gas exchange in all cells occurs directly with the external environment
D) those of humans, where there are four pumping chambers to drive blood flow




2) Organisms with a circulating body fluid that is distinct from the fluid that directly surrounds the body's cells are likely to have _____.
A) an open circulatory system
B) a closed circulatory system
C) a gastrovascular cavity
D) branched tracheae




3) In which of the following organisms does blood flow from the pulmocutaneous circulation to the heart before circulating through the rest of the body?
A) annelids
B) fishes
C) frogs
D) insects




4) The only vertebrates in which blood flows directly from respiratory organs to body tissues without first returning to the heart are the _____.
A) amphibians
B) fishes
C) mammals
D) reptiles




5) To adjust blood pressure independently in the capillaries of the gas-exchange surface and in the capillaries of the general body circulation, an organism would need a(n) _____.
A) open circulatory system
B) hemocoel
C) two-chambered heart
D) four-chambered heart




6) An anthropologist discovers the fossilized heart of an extinct animal. The evidence indicates that the organism's heart was large, was well-formed, and had four chambers, with no connection between the right and left sides. A reasonable conclusion supported by these observations is that the _____.
A) animal had evolved from birds
B) animal was endothermic and had a high metabolic rate
C) animal was most closely related to alligators and crocodiles
D) species had little to no need to regulate blood pressure




7) In an open circulatory system, blood is _____.
A) always inside of vessels and is under higher pressure than in closed circulatory systems
B) not always confined to blood vessels and is under higher pressure than in closed circulatory systems
C) always inside of vessels and is under lower pressure than in closed circulatory systems
D) not always confined to blood vessels and is under lower pressure than in closed circulatory systems




8) Circulatory systems compensate for _____.
A) temperature differences between the lungs and the active tissue
B) the slow rate at which diffusion occurs over large distances
C) the problem of communication systems involving only the nervous system
D) the need to cushion animals from trauma





9) Which of the following develops the greatest pressure on the blood in the mammalian aorta?
A) systole of the left atrium
B) diastole of the right ventricle
C) systole of the left ventricle
D) diastole of the right atrium



10) Which of the following is the correct sequence of blood flow in birds and mammals?
A) left ventricle → aorta → lungs → systemic circulation
B) vena cava → right atrium → right ventricle → pulmonary vein
C) pulmonary vein → left atrium → left ventricle → pulmonary circuit
D) vena cava → right atrium → right ventricle → pulmonary artery




11) A patient with a blood pressure of 120/75, a pulse rate of 70 beats/minute, a stroke volume of 70 mL/beat (milliliters per beat), and a respiratory rate of 25 breaths/minute will have a cardiac output of _____.
A) 1,000 mL/minute
B) 1,750 mL/minute
C) 2,800 mL/minute
D) 4,900 mL/minute




12) Damage to the sinoatrial node in humans _____.
A) would block conductance between the bundle branches and the Purkinje fibers
B) would have a negative effect on peripheral resistance
C) would disrupt the rate and timing of cardiac muscle contractions
D) would have a direct effect on blood pressure monitors in the aorta




13) A stroke volume of 70 mL/cycle in a heart with a pulse of 72 cycles per minute results in a cardiac output of about _____.
A) 5 liters per minute
B) 50 milliliters per minute
C) 0.5 liters per minute
D) 50 liters per minute




14) Atria contract _____.
A) just prior to the beginning of diastole
B) during diastole
C) immediately after systole
D) during systole



15) The greatest difference in the concentration of respiratory gases is found in which of the following pairs of mammalian blood vessels?
A) the pulmonary vein and the jugular vein
B) the veins from the right and left legs
C) the pulmonary artery and the inferior vena cava
D) the pulmonary vein and the aorta




16) A human red blood cell in an artery of the left arm is on its way to deliver oxygen to a cell in the thumb. To travel from the artery to the thumb and then back to the left ventricle, this red blood cell must pass through _____.
A) one capillary bed
B) two capillary beds
C) three capillary beds
D) four capillary beds




17) If a molecule of carbon dioxide released into the blood in your left toe is exhaled from your nose, it must pass through all of the following EXCEPT _____.
A) the pulmonary vein
B) an alveolus
C) the trachea
D) the right atrium





18) Among the following choices, which organism likely has the highest systolic pressure?
A) mouse
B) human
C) hippopotamus
D) giraffe




19) The velocity of blood flow is the lowest in capillaries because _____.
A) the capillaries have internal valves that slow the flow of blood
B) the diastolic blood pressure is too low to deliver blood to the capillaries at a high flow rate
C) the systemic capillaries are supplied by the left ventricle, which has a lower cardiac output than the right ventricle
D) the total cross-sectional area of the capillaries is greater than the total cross-sectional area of the arteries or any other part of the circulatory system



20) A species that has a normal resting systolic blood pressure of greater than 260 mm Hg is likely to be _____.
A) an animal that is small and compact, without the need to pump blood very far from the heart
B) a species that has very wide diameter veins
C) an animal that has a very long distance between its heart and its brain
D) an animal that makes frequent, quick motions




21) Small swollen areas in the neck, groin, and axillary region are associated with _____.
A) increased activity of the immune system
B) blood sugar that is abnormally high
C) dehydration
D) sodium depletion





22) What will be the long-term effect of blocking the lymphatic vessels associated with a capillary bed?
A) more fluid entering the venous capillaries
B) an increase in the blood pressure in the capillary bed
C) the accumulation of more fluid in the interstitial areas
D) the area of the blockage becoming abnormally small




23) Which of the following conditions would most likely be due to high blood pressure in a mammal?
A) bursting of blood vessels in capillary beds
B) inability of the right ventricle to contract
C) reversal of normal blood flow direction in arteries
D) destruction of red blood cells




24) Which of the following mechanisms are used to regulate blood pressure in the closed circulatory system of vertebrates?
I)   changing the force of heart contraction
II)  constricting and relaxing sphincters in the walls of arterioles
III)      adjusting the volume of blood contained in the veins
A) only I and II
B) only I and III
C) only II and III
D) I, II, and III



25) Blood is pumped at high pressures in arteries from the heart to ensure that all parts of the body receive adequate blood flow. Capillary beds, however, would hemorrhage under direct arterial pressures. How does the design of the circulatory network contribute to reducing blood pressure to avoid this scenario?
A) Blood flow through the capillaries is essentially frictionless, and this reduces the amount of pressure on their walls.
B) The total cross-sectional diameter of the arterial circulation increases with progression from artery to arteriole to capillary, leading to a reduced blood pressure.
C) Fluid loss from the arteries is high enough that pressure drops off significantly by the time blood reaches the capillaries.
D) Capillary beds have the thickest walls of any blood vessel to resist these high pressures.




Lymph hearts are pumping structures that drive lymph through the lymphatic system, returning it to the circulatory system at the large veins entering the heart. Researchers examined rate and strength of pumping of lymph hearts in two species of amphibians, a toad (Bufo marinus) and a frog (Rana catesbiana). During hemorrhage or dehydration, the volume of blood in the circulatory system falls. (E. A. DeGrauw and S. S. Hillman. 2004. General function and endocrine control of the posterior lymph hearts in Bufo marinus and Rana catesbiana. Physiological and Biochemical Zoology 77(4):594-600.)

26) Refer to the paragraph on lymph hearts. What effect would increasing lymph heart pressure have first?
A) Blood volume would increase.
B) Blood volume would decrease.
C) Hemorrhage would increase.
D) Hemorrhage would decrease.




27) If, during protein starvation, the osmotic pressure on the venous side of capillary beds drops below the hydrostatic pressure, then _____.
A) hemoglobin will not release oxygen
B) fluids will tend to accumulate in tissues
C) the pH of the interstitial fluids will increase
D) plasma proteins will escape through the endothelium of the capillaries




28) Large proteins such as albumin remain in capillaries rather than diffusing out, resulting in the _____.
A) loss of osmotic pressure in the capillaries
B) development of an osmotic pressure difference across capillary walls
C) loss of fluid from capillaries
D) increased diffusion of hemoglobin



29) The production of red blood cells is stimulated by _____.
A) low-density lipoproteins
B) immunoglobulins
C) erythropoietin
D) epinephrine





30) To become bound to hemoglobin for transport in a mammal, atmospheric molecules of oxygen must cross _____.
A) one membrane—that of the lining in the lungs—and then bind directly to hemoglobin, a protein dissolved in the plasma of the blood
B) two membranes—in and out of the cell lining the lung—and then bind directly to hemoglobin, a protein dissolved in the plasma of the blood
C) four membranes—in and out of the cell lining the lung, in and out of the endothelial cell lining an alveolar capillary—and then bind directly to hemoglobin, a protein dissolved in the plasma of the blood
D) five membranes—in and out of the cell lining the lung, in and out of the endothelial cell lining an alveolar capillary, and into the red blood cell—to bind with hemoglobin




31) The diagnosis of hypertension in adults is based on the _____.
A) measurement of fatty deposits on the endothelium of arteries
B) measurement of the LDL/HDL ratio in peripheral blood
C) percentage of blood volume made up of platelets
D) blood pressure being greater than 140 mm Hg systolic and/or greater than 90 mm Hg diastolic




32) Cyanide poisons mitochondria by blocking the final step in the electron transport chain. Human red blood cells placed in an isotonic solution containing cyanide are likely to _____.
A) retain the normal cell shape, but the mitochondria will be poisoned
B) lyse as the cyanide concentration increases inside the cell
C) switch to anaerobic metabolism
D) be unaffected




33) A normal event in the process of blood clotting is the _____.
A) production of erythropoietin
B) conversion of fibrin to fibrinogen
C) activation of prothrombin to thrombin
D) synthesis of hemoglobin




34) You cut your finger, and after putting pressure on the wound for several minutes, you notice that it is still bleeding profusely. What may be the problem?
A) Platelets are not functioning properly, or there are too few to be effective.
B) Mast cells are not releasing their chemical messengers.
C) There are too many antigens to allow clotting.
D) Hemoglobin levels are too high to allow clotting.




35) The hormone that stimulates the production of red blood cells, and the organ where this hormone is synthesized, are _____.
A) growth hormone and pancreas, respectively
B) erythropoietin and kidney, respectively
C) cortisol and adrenal gland, respectively
D) acetylcholine and bone marrow, respectively




36) Countercurrent exchange is evident in the flow of _____.
A) water across the gills of a fish and the blood within those gills
B) blood in the dorsal vessel of an insect and that of air within its tracheae
C) air within the primary bronchi of a human and the blood within the pulmonary veins
D) water across the skin of a frog and the blood flow within the ventricle of its heart




37) Countercurrent exchange in the fish gill helps to maximize _____.
A) blood pressure
B) diffusion
C) active transport
D) osmosis





38) Which of the following statements comparing respiration in fish and in mammals is correct?
A) The respiratory medium for fish carries more oxygen than the respiratory medium of mammals.
B) A countercurrent exchange mechanism between the respiratory medium and blood flow is seen in mammals but not in fish.
C) The movement of the respiratory medium in mammals is bidirectional, but in fish it is unidirectional.
D) In blood, oxygen is primarily transported by plasma in fish, but by red blood cells in mammals.



39) Flying insects typically _____.
A) decrease metabolism as much as 200-fold during flight
B) switch from diffusion of tracheal gases to active transport during flight
C) utilize high numbers of mitochondria in flight muscles
D) generate fuel molecules from catabolism of carbon dioxide




40) When the air in a testing chamber is specially mixed so that its oxygen content is 10 percent and its overall air pressure is 400 mm Hg, then  is _____.
A) 400 mm Hg
B) 82 mm Hg
C) 40 mm Hg
D) 4 mm Hg




41) The sun shining on a tidal pool during a hot day heats the water. As some water evaporates, the pool becomes saltier, causing _____.
A) an increase in its carbon dioxide content
B) a decrease in its oxygen content
C) an increase in its ability to sustain aerobic organisms
D) a decrease in the water's density





42) An oil-water mixture works as an insecticidal spray against mosquitoes and other insects because it _____.
A) blocks the openings into the tracheal system
B) interferes with gas exchange across the capillaries
C) clogs their bronchi
D) prevents gases from leaving the atmosphere




43) Atmospheric pressure at sea level is equal to a column of 760 mm Hg. Oxygen makes up 21 percent of the atmosphere by volume. The partial pressure of oxygen () in such conditions is _____.
A) 160 mm Hg
B) 16 mm Hg
C) 21/760
D) 760/21



44) Some human infants, especially those born prematurely, suffer serious respiratory failure because of _____.
A) the sudden change from the uterine environment to the air
B) the overproduction of surfactants
C) lung collapse due to inadequate production of surfactant
D) mutations in the genes involved in lung formation




45) At the summit of a high mountain, the atmospheric pressure is 380 mm Hg. If the atmosphere is still composed of 21percent oxygen, then the partial pressure of oxygen at this altitude is about _____.
A) 80 mm Hg
B) 160 mm Hg
C) 380 mm Hg
D) 760 mm Hg





46) Compared with the interstitial fluid that bathes active muscle cells, blood reaching these muscle cells in arteries has a _____.
A) higher
B) greater bicarbonate concentration
C) lower pH
D) lower osmotic pressure




47) A rabbit taken from a meadow near sea level and moved to a meadow high on a mountainside would have some trouble breathing. Why?
A) The percentage of oxygen in the air at high elevations is lower than at sea level.
B) The percentage of oxygen in the air at high elevations is higher than at sea level.
C) The partial pressure of oxygen in the air at high elevations is lower than at sea level.
D) The partial pressure of oxygen in the air at high elevations is higher than at sea level.




48) What would be the consequences if we were to reverse the direction of water flow over the gills of a fish, moving water inward past the operculum, past the gills, the out the mouth? This reversal of water flow would _____.
A) reduce efficiency of gas exchange
B) change the exchange of gases in the body from carbon dioxide out and oxygen in to carbon dioxide in and oxygen out
C) increase the efficiency of gas exchange



49) Under identical atmospheric conditions, freshwater _____.
A) has more oxygen than seawater
B) has less oxygen than seawater
C) can hold 10-40 times more carbon dioxide than air
D) can hold 10-40 times more oxygen than air





50) Which of the following statements comparing respiration in fish and in mammals is correct?
A) The respiratory medium for fish carries more oxygen than the respiratory medium of mammals.
B) A countercurrent exchange mechanism between the respiratory medium and blood flow is seen in mammals but not in fish.
C) The movement of the respiratory medium in mammals is bidirectional, but in fish it is unidirectional.
D) In blood, oxygen is primarily transported by plasma in fish, but by red blood cells in mammals.




51) How has the avian lung adapted to the metabolic demands of flight?
A) Airflow through the avian lung is bidirectional like in mammals.
B) There is more dead space within the avian lung so that oxygen can be stored for future use.
C) Countercurrent circulation is present in the avian lung.
D) Gas exchange occurs during both inhalation and exhalation.




52) Carbon dioxide levels in the blood and cerebrospinal fluid affect pH. This enables the organism to sense a disturbance in gas levels as _____.
A) the brain directly measures and monitors oxygen levels and causes breathing changes accordingly
B) the medulla oblongata, which is in contact with cerebrospinal fluid, monitors pH and uses this measure to control breathing
C) the brain alters the pH of the cerebrospinal fluid to force the animal to retain more or less carbon dioxide
D) stretch receptors in the lungs cause the medulla oblongata to speed up or slow breathing



53) A person with a tidal volume of 450 mL (milliliters), a vital capacity of 4000 mL, and a residual volume of 1000 mL would have a potential total lung capacity of _____.
A) 1450 mL
B) 4000 mL
C) 4450 mL
D) 5000 mL





54) During most daily activities, the human respiration rate is most closely linked to the blood levels of _____.
A) nitrogen
B) oxygen
C) carbon dioxide
D) carbon monoxide




55) An decrease from pH 7.4 to pH 7.2 causes hemoglobin to _____.
A) release all bound carbon dioxide molecules
B) bind more oxygen molecules
C) increase its binding of H+
D) give up more of its oxygen molecules




56) The Bohr shift on the oxygen-hemoglobin dissociation curve is produced by changes in _____.
A) the partial pressure of oxygen
B) hemoglobin concentration
C) temperature
D) pH




57) Most of the carbon dioxide produced by humans is _____.
A) converted to bicarbonate ions by an enzyme in red blood cells
B) bound to hemoglobin
C) transported in the erythrocytes as carbonic acid
D) simply dissolved in the plasma




58) Which of the following events would be predicted by the Bohr shift effect as the amount of carbon dioxide released from your tissues into the blood capillaries increases? The amount of oxygen in _____.
A) arterial blood would increase
B) arterial blood would decrease
C) venous blood would increase
D) venous blood would decrease




59) You are a physician, and you are seeing a patient who complains of abnormal fatigue during exercise. You find that the immediate problem is a buildup of carbon dioxide in the tissues. What is the most likely cause?
A) abnormally shaped platelets
B) abnormal carbonic anhydrase
C) abnormal hemoglobin
D) not enough hemoglobin




60) Carbonic anhydrase inhibitors cause less movement of carbonic acid toward carbon dioxide production and are used as a prophylactic treatment of altitude sickness. Altitude sickness occurs when a hiker ascends to altitudes where the density of oxygen is low. How does this decrease the symptoms of high altitude sickness?
A) The excess hydrogen ions are excreted in the urine and the resulting loss of acidity increases respiration rate.
B) The excess bicarbonate ions are excreted in the urine and the resulting loss of blood pressure increases respiration rate.
C) The excess bicarbonate ions are excreted in the urine and the resulting increase in blood acidity leads to an increase in ventilation.
D) The excess bicarbonate ions in the blood increase the affinity of hemoglobin for oxygen.


 Campbell Biology, 10e (Reece)
Chapter 43   The Immune System

1) Innate immunity _____.
A) is activated immediately upon infection
B) depends on an infected animal's previous exposure to the same pathogen
C) is based on recognition of antigens that are specific to different pathogens
D) is found only in vertebrate animals




2) A fruit fly, internally infected by a potentially pathogenic fungus, is protected by its _____.
A) immunoglobulins
B) antibodies
C) antimicrobial peptides
D) B cells




3) Engulfing-phagocytic cells of innate immunity of vertebrates include _____.
I)    neutrophils
II)  macrophages
III) dendritic cells
IV) natural killer cells
A) I and III
B) II and IV
C) I and IV
D) I, II, and III




4) The cells and signaling molecules involved in the initial stages of the inflammatory response are _____.
A) phagocytes and chemokines
B) dendritic cells and interferons
C) mast cells and histamines
D) lymphocytes and interferons





5) Inflammatory responses typically include _____.
A) increased activity of phagocytes in an inflamed area
B) reduced permeability of blood vessels to conserve plasma
C) release of substances to decrease the blood supply to an inflamed area
D) inhibiting the release of white blood cells from bone marrow



6) Mammals have Toll-like receptors (TLRs) that can recognize a kind of macromolecule that is absent from vertebrates but present in or on certain groups of pathogens, such as viral _____.
A) double-stranded DNA
B) double-stranded RNA
C) glycoproteins
D) phospholipids




7) Septic shock, a systemic response including high fever and low blood pressure, is a response to _____.
A) certain bacterial infections
B) specific forms of viruses
C) the presence of natural killer cells
D) increased production of neutrophils




8) The cells involved in innate immunity, whose absence increases the chances of developing malignant tumors, are _____.
A) cytotoxic T cells
B) natural killer cells
C) macrophages
D) B cells




Mutant fruit flies that make only one antimicrobial peptide were tested for survival after infection with Neurospora crassa fungi or with Micrococcus luteus bacteria.

    

9) The results shown in the graphs support the hypothesis that _____.
A) adding the defensin gene to such mutants protects them from death by fungal infection
B) adding the drosomycin gene to such mutants protects them from death by fungal infection
C) wild-type flies with the full set of genes for antimicrobial peptides are highly susceptible to these infective agents
D) the presence of any single antimicrobial peptide protects against both infective agents




10) You and a friend were in line for a movie when you noticed the woman in front of you sneezing and coughing. Both of you were equally exposed to the woman's virus, but over the next few days, only your friend acquired flu-like symptoms and was ill for almost a week before recovering. Which one of the following is a logical explanation for this?
A) Your friend had antibodies to that virus.
B) You had an adaptive immunity to that virus.
C) Your friend had an autoimmune disorder.
D) Your friend had allergies.




11) A boy falls while riding his bike. A scrape on his hand almost immediately begins to bleed and becomes red, warm, and swollen. What response is occurring?
A) inflammatory response
B) lytic response
C) adaptive immune response
D) autoimmune response




12) Acidity in human sweat is an example of _____.
A) cell-mediated immune responses
B) acquired immunity
C) adaptive immunity
D) innate immunity




13) The eyes and the respiratory tract are both protected against infections by _____.
A) interferons produced by immune cells
B) the secretion of complement proteins
C) the release of slightly alkaline secretions
D) the secretion of lysozyme onto their surfaces




14) The complement system is _____.
A) a set of proteins involved in innate but not acquired immunity
B) a group of proteins that includes interferons and interleukins
C) a group of antimicrobial proteins that act together in a cascade fashion
D) a set of proteins that act individually to attack and lyse microbes




15) Bacteria entering the body through a small cut in the skin _____.
A) inactivate the erythrocytes
B) stimulate apoptosis of nearby body cells
C) stimulate release of interferons
D) activate a group of proteins called complement




16) Mucus occurs in both the respiratory and digestive tracts. What is its main immunological function?
A) sweeping away debris
B) physically trapping pathogens
C) destruction of pathogens because it is acidic
D) increasing oxygen absorption




17) Within a differentiated B cell, the rearrangement of DNA sequences between variable regions and joining regions is accomplished by a(n)_____.
A) RNA polymerase
B) reverse transcriptase
C) epitopase
D) recombinase




18) Clonal selection and differentiation of B cells activated by antigen exposure leads to the production of _____.
A) large quantities of the antigen initially recognized
B) vast numbers of B cells with random antigen-recognition receptors
C) long-lived erythrocytes that can later secrete antibodies for the antigen
D) short-lived plasma cells that secrete antibodies for the antigen




19) A newborn who is accidentally given a drug that destroys the thymus would most likely _____.
A) lack innate immunity
B) be unable to genetically rearrange antigen receptors
C) be unable to differentiate and mature T cells
D) have a reduced number of B cells and be unable to form antibodies





20) Clonal selection is an explanation for how _____.
A) V, J, and C gene segments are rearranged
B) an antigen can provoke production of high levels of specific antibodies
C) HIV (human immunodeficiency virus) can disrupt the immune system
D) macrophages can recognize specific T cells and B cells



21) An immunoglobulin (Ig) molecule, of whatever class, with regions symbolized as C or V, H or L, has a light chain made up of _____.
A) one C region and one V region
B) one H region and one L region
C) three H regions and one L region
D) two C regions and two V regions




22) Immunological memory accounts for _____.
A) the human body's ability to distinguish self from non-self
B) the observation that some strains of the pathogen that causes dengue fever cause more severe disease than others
C) the ability of a helper T cell to signal B cells via cytokines
D) the ancient observation that someone who had recovered from the plague could safely care for those newly diseased

Bloom's Taxonomy:  Synthesis/Evaluation


Use the following information to answer the question(s) below.

An otherwise healthy student in your class is infected with EBV, the virus that causes infectious mononucleosis. The same student had already been infected when she was a child, at which time she had merely experienced a mild sore throat and swollen lymph nodes in her neck. This time, though infected, she does not get sick.

23) The EBV antigen fragments will be presented by the virus-infected cells along with _____.
A) a complement
B) antibodies
C) class I MHC molecules
D) class II MHC molecules





24) Vaccination increases the number of _____.
A) lymphocytes with receptors that can bind to the pathogen
B) epitopes that the immune system can recognize
C) macrophages specific for a pathogen
D) major histocompatability (MHC) molecules that can present an antigen

Bloom's Taxonomy:  Synthesis/Evaluation

25) If a patient is missing B and T cells, what would be absent from the immune response?
A) memory
B) lysozymes
C) cytokines
D) defense against bacteria




26) Lymphocytes mature in the _____.
I)   spleen
II)  thymus
III)      bone marrow
A) only I and III
B) only I and II
C) only II and III
D) I, II, and III




27) Which of the following statements are fundamental to the clonal-selection theory of how the adaptive immune system functions?
I)   Each lymphocyte has a unique membrane receptor that recognizes one antigen.
II)  When the lymphocyte binds an antigen, it is activated and begins dividing to form many identical copies of itself.
III)      Cloned lymphocytes have slight differences and are selected by the spleen for removal if they do not bind an antigen.
IV)      Cloned cells descend from an activated lymphocyte and persist even after the pathogen is eliminated.
A) only I and III
B) only II and IV
C) only I, II, and IV
D) only II, III, and IV





28) What major advantage is conveyed by having a system of adaptive immunity?
A) It enables a rapid defense against an antigen that has been previously encountered.
B) It enables an animal to counter most pathogens almost instantly the first time they are encountered.
C) It results in effector cells with specificity for a large number of antigens.
D) It allows for the destruction of antibodies.



29) Which of the following is a difference between B cells and T cells?
A) One has a major role in antibody production, while the other has a major role in cytotoxicity.
B) One binds a receptor called BCR (B-cell receptor), while the other recognizes a receptor called TCR (T-cell receptor).
C) B cells are activated by free-floating antigens in the blood or lymph. T cells are activated by membrane-bound antigens.
D) T cells are produced in the thymus and B cells are produced in the bone marrow.




30) A certain cell type has existed in the blood and tissue of its vertebrate host's immune system for over twenty years. One day, it recognizes a newly arrived antigen and binds to it, subsequently triggering a secondary immune response in the body. Which of the following cell types most accurately describes this cell?
A) plasma cell
B) thyroid cell
C) memory cell
D) macrophage




31) Which of the following statements about epitopes are correct?
I)   B-cell receptors bind to epitopes.
II)  T-cell receptors bind to epitopes.
III)      There can be 10 or more different epitopes on each antigen.
IV)      There is a one-to-one correspondence between antigen and epitope.
A) only I and III
B) only II and IV
C) only I, II, and III
D) only II, III, and IV





32) Which of the following pairs of proteins shares the most overall similarity in structure?
A) B-cell receptors and T-cell receptors
B) B-cell receptors and antibodies
C) T-cell receptors and antibodies
D) antibodies and antigens



33) What type of immunity is associated with breast feeding?
A) innate immunity
B) active immunity
C) passive immunity
D) cell-mediated immunity




34) Select the pathway that would lead to the activation of cytotoxic T cells.
A) B cell contact antigen → helper T cell is activated → clonal selection occurs
B) body cell becomes infected with a virus → new viral proteins appear → class I MHC molecule-antigen complex displayed on cell surface
C) complement is secreted → B cell contacts antigen → helper T cell activated → cytokines released
D) cytotoxic T cells → class II MHC molecule-antigen complex displayed → cytokines released → cell lysis




35) Arrange in the correct sequence these components of the mammalian immune system as it first responds to a pathogen.
I)   Pathogen is destroyed.
II) Lymphocytes secrete antibodies.
III)      Antigenic determinants from pathogen bind to antigen receptors on lymphocytes.
IV)      Lymphocytes specific to antigenic determinants from pathogen become numerous.
V)  Only memory cells remain.
A) I → III → II → IV → V
B) II → I → IV → III → V
C) IV → II → III → I → V
D) III → IV → II → I → V





36) A nonfunctional CD4 protein on a helper T cell would result in the helper T cell being unable to _____.
A) respond to T-independent antigens
B) lyse tumor cells
C) stimulate a cytotoxic T cell
D) interact with a class II MHC-antigen complex



37) CD4 and CD8 are _____.
A) proteins secreted by antigen-presenting cells
B) receptors present on the surface of natural killer cells
C) molecules present on the surface of T cells where they interact with major histocompatability (MHC) molecules
D) molecules on the surface of antigen-presenting cells where they enhance B cell activity




38) T cells of the immune system include _____.
A) CD4, CD8, and plasma cells
B) cytotoxic and helper cells
C) plasma, antigen-presenting, and memory cells
D) lymphocytes, macrophages, and dendritic cells




39) B cells interacting with helper T cells are stimulated to differentiate when _____.
A) B cells produce IgE antibodies
B) B cells release cytokines
C) cytotoxic T cells present the class II MHC molecule-antigen complex on their surface
D) helper T cells release cytokines




40) When antibodies bind antigens, the clumping of antigens results from _____.
A) the antibody having at least two binding regions
B) disulfide bridges between the antigens
C) bonds between class I and class II MHC molecules
D) denaturation of the antibodies





41) Phagocytosis of microbes by macrophages is enhanced by _____.
I)   the binding of antibodies to the surface of microbes
II)  antibody-mediated agglutination of microbes
III)      the release of cytokines by activated B cells
A) only I and II
B) only II and III
C) only I and III
D) I, II, and, III



42) Naturally acquired passive immunity can result from the _____.
A) injection of vaccine
B) ingestion of interferon
C) placental transfer of antibodies
D) absorption of pathogens through mucous membranes




43) Jenner's successful use of cowpox virus as a vaccine against the smallpox virus was due to the fact that _____.
A) the immune system responds nonspecifically to antigens
B) the cowpox virus made antibodies in response to the presence of smallpox
C) there are some epitopes (antigenic determinants) common to both pox viruses
D) cowpox and smallpox are caused by the same virus




44) An individual who has been bitten by a poisonous snake that has a fast-acting toxin would likely benefit from _____.
A) vaccination with a weakened form of the toxin
B) injection of antibodies to the toxin
C) injection of interleukin-1
D) injection of interferon





45) For the successful development of a vaccine to be used against a pathogen, it is necessary that _____.
A) the surface antigens of the pathogen stay the same
B) all of the surface antigens on the pathogen be identified
C) the pathogen has only one epitope
D) the major histocompatability (MHC) molecules are heterozygous




46) The switch of one B cell from producing one class of antibody to another class of antibody that is responsive to the same antigen is due to _____.
A) the rearrangement of V region genes in that clone of responsive B cells
B) a switch in the kind of antigen-presenting cell that is involved in the immune response
C) a patient's reaction to the first kind of antibody made by the plasma cells
D) the rearrangement of immunoglobulin heavy-chain C region DNA

Bloom's Taxonomy:  Synthesis/Evaluation

47) The number of major histocompatability (MHC) protein combinations possible in a given population is enormous. However, an individual in that diverse population has a far more limited array of MHC molecules because _____.
A) the MHC proteins are made from several different gene regions that are capable of rearranging in a number of ways
B) MHC proteins from one individual can only be of class I or class II
C) each of the MHC genes has a large number of alleles, but each individual only inherits two for each gene
D) once a B cell has matured in the bone marrow, it is limited to two MHC response categories

Bloom's Taxonomy:  Synthesis/Evaluation


48) A bone marrow transplant may not be appropriate from a given donor (Jane) to a given recipient (Jane's cousin Bob), even though Jane has previously given blood for one of Bob's needed transfusions, because _____.
A) even though Jane's blood type is a match to Bob's, her major histocompatability (MHC) proteins may not be a match
B) a blood type match is less stringent than a match required for transplant because blood is more tolerant of change
C) for each gene, there is only one blood allele but many tissue alleles
D) Jane's MHC class II genes are not expressed in bone marrow





49) An immune response to a tissue graft will differ from an immune response to a bacterium because _____.
A) MHC molecules of the donor may stimulate rejection of the graft tissue, but bacteria lack MHC molecules
B) the tissue graft, unlike the bacterium, is isolated from the circulation and will not enter into an immune response
C) a bacterium cannot escape the immune system by replicating inside normal body cells
D) the graft will stimulate an autoimmune response in the recipient



Use the following information to answer the question(s) below.

An otherwise healthy student in your class is infected with EBV, the virus that causes infectious mononucleosis. The same student had already been infected when she was a child, at which time she had merely experienced a mild sore throat and swollen lymph nodes in her neck. This time, though infected, she does not get sick.

50) Her immune system's recognition of the second infection involves memory _____.
A) helper T cells
B) natural killer cells
C) plasma cells
D) cytotoxic T cells




51) Which of the following should be the same in identical twins?
A) the set of antibodies produced
B) the set of major histocompatability (MHC) molecules produced
C) the set of T cell antigen receptors produced
D) the susceptibility to a particular virus




52) Which of the following is crucial to activation of the adaptive immune response?
A) memory cells
B) presentation of MHC (major histocompatibility complex)-antigen complex on a cell surface
C) somatic hypermutation
D) phagocytosis of antibody-antigen complex by macrophages in the blood (the humoral response)





53) Which of the following components of the immune system destroys bacteria in a way similar to an antitank weapon destroying armored military tanks by punching holes in the wall of the bacteria?
A) complement protein
B) macrophages
C) plasma cells
D) major histocompatibility complex proteins



54) Yearly vaccination of humans for influenza viruses is necessary because _____.
A) of an increase in immunodeficiency diseases
B) the flu can generate anaphylactic shock
C) surviving the flu one year exhausts the immune system to nonresponsiveness the second year
D) rapid mutation in flu viruses alters the surface proteins in infected host cells




55) A patient who has a high level of mast cell activity, dilation of blood vessels, and acute drop in blood pressure is likely suffering from _____.
A) an autoimmune disease
B) a typical skin allergy (contact dermatitis) that can be treated by antihistamines
C) an organ transplant, such as a skin graft
D) anaphylactic shock immediately following exposure to an allergen




56) The ability of some viruses to remain inactive (latent) for a period of time is exemplified by _____.
A) influenza, a particular strain of which returns every 10-20 years
B) herpes simplex viruses (oral or genital) whose reproduction is triggered by physiological or emotional stress in the host
C) Kaposi's sarcoma, which causes a skin cancer in people with AIDS but rarely in those not infected by HIV
D) the virus that causes a form of the common cold, which recurs in patients many times in their lives





57) A patient complaining of watery, itchy eyes and sneezing after being given a flower bouquet as a birthday gift should first be treated with _____.
A) a vaccine
B) sterile pollen
C) antihistamines
D) monoclonal antibodies



58) Which of the following would help a virus avoid triggering an effective adaptive immune response?
I)   having frequent mutations in genes for surface proteins
II)  building the viral shell from host proteins
III)      producing proteins very similar to those of other viruses
IV)      infecting and killing helper T cells
A) only I and III
B) only I, II, and IV
C) only I, II, and III
D) only II, III, and IV

Bloom's Taxonomy:  Synthesis/Evaluation


59) Which of the following is the best definition of autoimmune disease?
A) a condition in which B cells and T cells respond independently to antigens and do not interact correctly
B) a condition in which the adaptive immune system fails to recognize the second infection by the same antigen
C) a condition in which self molecules are treated as non-self
D) a condition in which the immune system creates random antibodies without being triggered by an antigen




60) Which of the following would prevent allergic attacks?
A) blocking the attachment of the IgE antibodies to the mast cells
B) blocking the antigenic determinants of the IgM antibodies
C) reducing the number of helper T cells in the body
D) reducing the number of cytotoxic cells





61) In a humoral or antibody-mediated immune response, specific B cells are stimulated by Helper T cells to transform into plasma cells that secrete antibodies. What would be an important feature added to B cells In this transition process?
A) Duplication of specific gene sequences for the appropriate antibody.
B) Increased rough endoplasmic reticulum in order to have the surface area needed for antibody production.
C) Duplication of lysosomes in order to store the antibodies before transport.


 Campbell Biology, 10e (Reece)
Chapter 44   Osmoregulation and Excretion

1) The force driving simple diffusion is _____, while the energy source for active transport is _____.
A) the concentration gradient; ADP
B) the concentration gradient; ATP
C) transmembrane pumps; electron transport
D) phosphorylated protein carriers; ATP




2) To maintain homeostasis freshwater fish must _____.
A) excrete large quantities of electrolytes
B) consume large quantities of water
C) excrete large quantities of water
D) take in electrolytes through simple diffusion




3) Single-celled Paramecium live in pond water (a hypotonic environment). They have a structural feature, a contractile vacuole, which enables them to osmoregulate. If you observed them in the following solutions, at which sucrose concentration (in millimolars, mM) would you expect the contractile vacuole to be most active?
A) 0.0 mM sucrose
B) 0.05 mM saline
C) 0.08 mM sucrose
D) 1.0 mM saline




4) Sharks live in seawater. Their tissues are isotonic to seawater, but their concentrations of sodium ions, potassium ions, and chloride ions in cells and extracellular fluids are similar to those of freshwater fishes. How is that possible?
A) Urea and trimethylamine oxide contribute to intra- and extracellular osmolarity in shark tissues.
B) Metabolic intermediates of sharks tie up intracellular chloride and potassium ions.
C) Their blood is hypotonic to their tissues.
D) They excrete large quantities of electrolytes.




5) Hagfish (Eptatretus cirrhauts) are a jawless marine vertebrate that are isotonic with their environment and are considered to be osmoconformers. How might this interesting adaptation limit the habitat that the hagfish can tolerate?
A) Hagfish are not limited by salinity.
B) Osmoconformers do not face the same pressures as osmoregulators and can live in any marine environment.
C) Individual hagfish will adapt to different salinities over their lifetime and, therefore, can inhabit any marine environment.
D) Hagfish habitat is limited by the salinity of the environment.




6) Tissues of sharks are isotonic to seawater, but their concentrations of sodium ions, potassium ions, and chloride ions in cells and extracellular fluids are similar to those of freshwater fishes. What can you infer about the movement of sodium and chloride in these animals?
A) To maintain homeostasis of sodium and chloride levels, the shark must take up additional sodium and chloride from seawater.
B) Sodium and chloride will diffuse into shark gills from seawater down their concentration gradient.
C) Sharks conserve sodium and chloride, limiting excretion.
D) Sodium and chloride must be eliminated through the gills.




7) What role do chloride cells play in osmoregulation of marine fish with bony skeletons?
A) They actively transport chloride into the gills.
B) They mediate the movement of salt from seawater through their gills.
C) They are involved in excretion of excess salt.
D) They actively transport salt across the basolateral membrane of the rectal gland.




8) Salmon eggs hatch in freshwater. The fish then migrate to the ocean (a hypertonic solution) and, after several years of feeding and growing, return to freshwater to breed. How can these organisms make the transition from freshwater to ocean water and back to freshwater?
A) The rectal gland functions in the ocean water, and chloride cells function in freshwater.
B) Different gill cells are involved in osmoregulation in freshwater than in salt water.
C) Salmon in freshwater excrete dilute urine, and salmon in salt water secrete concentrated urine.
D) Their metabolism changes in salt water to degrade electrolytes.




9) Terrestrial organisms lose water through evaporation. In what ecosystem might an entomologist find a good study organism to examine the prevention of water loss?
A) wet rain forest
B) desert
C) prairie
D) chaparral




10) A necropsy (postmortem analysis) of a marine sea star that died after it was mistakenly placed in fresh water would likely show that it died because _____.
A) it was stressed and needed more time to acclimate to the new conditions
B) it was so hypertonic to the fresh water that it could not osmoregulate
C) its contractile vacuoles ruptured
D) its cells dehydrated and lost the ability to metabolize




11) The body fluids of an osmoconformer would be _____ with its _____ environment
A) isoosmotic; freshwater
B) hyperosmotic; saltwater
C) isoosmotic; saltwater
D) hypoosmotic; saltwater




12) Compared to the seawater around them, most marine invertebrates are _____.
A) hyperosmotic
B) hypoosmotic
C) isoosmotic
D) hyperosmotic and isoosmotic




13) The fluid with the highest osmolarity is _____.
A) distilled water
B) plasma in birds
C) plasma in mammals
D) seawater in a tidal pool




14) A human who has no access to fresh water but is forced to drink seawater instead will _____.
A) thrive under such conditions, as long as he has lived at the ocean most of his life
B) excrete more water molecules than taken in, because of the high load of ion ingestion
C) develop structural changes in the kidneys to accommodate the salt overload
D) risk becoming overhydrated within twelve hours




15) Unlike most bony fishes, sharks maintain body fluids that are isoosmotic to seawater, so they are considered by many to be osmoconformers. Nonetheless, these sharks osmoregulate at least partially by _____.
A) using their gills and kidneys to rid themselves of sea salts
B) monitoring dehydration at the cellular level with special gated aquaporins
C) tolerating high urea concentrations that are balanced with internal salt concentrations to seawater osmolarity
D) synthesizing trimethylamine oxide, a chemical that binds and precipitates salts inside cells




16) The necropsy (postmortem analysis) of a freshwater fish that died after being placed accidentally in saltwater would likely show that _____.
A) loss of water by osmosis from cells in vital organs resulted in cell death and organ failure
B) high amounts of salt had diffused into the fish's cells, causing them to swell and lyse
C) the kidneys were not able to keep up with the water removal necessary in this hyperosmotic environment, creating an irrevocable loss of homeostasis
D) the gills became encrusted with salt, resulting in inadequate gas exchange and a resulting asphyxiation




17) Which of the following animals generally has the lowest volume of urine production?
A) a vampire bat
B) a salmon in fresh water
C) a marine bony fish
D) a shark inhabiting the Mississippi River




18) One of the waste products that accumulates during cellular functions is carbon dioxide. It is removed via the respiratory system. What is another waste product that accumulates during normal physiological functions in vertebrates?
I)   ammonia
II)  uric acid
III)      urea
A) only I and III
B) only II and III
C) only I and II
D) I, II, and III




19) Urea is produced in the _____.
A) liver from NH3 and carbon dioxide
B) liver from glycogen
C) kidneys from glycerol and fatty acids
D) bladder from uric acid and water




20) Urea is _____.
A) insoluble in water
B) the primary nitrogenous waste product of humans
C) the primary nitrogenous waste product of most birds
D) the primary nitrogenous waste product of most aquatic invertebrates




21) Which nitrogenous waste has the greatest number of nitrogen atoms?
A) ammonia
B) ammonium ions
C) urea
D) uric acid





22) Ammonia is likely to be the primary nitrogenous waste in living conditions that include _____.
A) lots of fresh water flowing across the gills of a fish
B) lots of seawater, such as a bird living in a marine environment
C) a terrestrial environment, such as that supporting crickets
D) a moist system of burrows, such as those of naked mole rats



23) Excessive formation of uric acid crystals in humans leads to _____.
A) a condition called diabetes, where excessive urine formation occurs
B) a condition of insatiable thirst and excessive urine formation
C) gout, a painful inflammatory disease that primarily affects the joints
D) osteoarthritis, an inevitable consequence of aging




24) Ammonia _____.
A) is soluble in water
B) has low toxicity relative to urea
C) is metabolically more expensive to synthesize than urea
D) is the major nitrogenous waste excreted by insects




25) The advantage of excreting nitrogenous wastes as urea rather than as ammonia is that _____.
A) urea can be exchanged for Na+
B) urea is less toxic than ammonia
C) urea does not affect the osmolar gradient
D) less nitrogen is removed from the body




26) In animals, nitrogenous wastes are produced mostly from the catabolism of _____.
A) starch and cellulose
B) triglycerides and steroids
C) proteins and nucleic acids
D) phospholipids and glycolipids





27) Birds secrete uric acid as their nitrogenous waste because uric acid _____.
A) is readily soluble in water
B) is metabolically less expensive to synthesize than other excretory products
C) requires little water for nitrogenous waste disposal, thus reducing body mass
D) can be reused by birds as a protein source



28) Among the following choices, the most concentrated urine is excreted by _____.
A) frogs
B) kangaroo rats
C) humans
D) freshwater bass




29) African lungfish, which are often found in small, stagnant pools of fresh water, produce urea as a nitrogenous waste. What is the advantage of this adaptation?
A) Urea takes less energy to synthesize than ammonia.
B) Small, stagnant pools do not provide enough water to dilute the toxic ammonia.
C) The highly toxic urea makes the pool uninhabitable to potential competitors.
D) Urea makes lungfish tissue hypoosmotic to the pool.




30) Which of the following most accurately describes selective permeability?
A) An input of energy is required for transport.
B) Lipid-soluble molecules pass through a membrane.
C) There must be a concentration gradient for molecules to pass through a membrane.
D) Only certain molecules can cross a cell membrane.





31) Through studies of insect Malpighian tubules, researchers found that K+ accumulated on the inner face of the tubule, against its concentration gradient. What can you infer about the mechanism of transport?
A) Potassium transport is a passive process.
B) Movement of potassium into the lumen of the Malpighian tubules is an energy-requiring process.
C) Potassium moves out of the tubules at a faster rate than it moves into the lumen of the tubules.
D) Sodium ions will follow potassium ions.




32) A potassium ion gradient is set up in insect Malpighian tubules through an active transport process. As a result, potassium concentration is higher in the lumen of the tubules than in hemolymph. How would the potassium gradient affect water movement?
A) Water would be forced out of the lumen of the Malpighian tubules through an osmotic gradient.
B) The potassium gradient would have no effect on water movement.
C) There would be a net movement of water into the lumen of the tubules.
D) Water would be conserved, forming a hypertonic solution in the Malpighian tubules.



33) Why are the renal artery and vein critical to the process of osmoregulation in vertebrates?
A) The kidneys require constant and abnormally high oxygen supply to function.
B) The renal artery delivers blood with nitrogenous waste to the kidney and the renal vein brings blood with less nitrogenous wastes away from the kidneys.
C) The kidneys require higher than normal levels of hormones.
D) The renal artery and vein are the main pathways regulating how much is produced by the kidneys.




34) The figure above shows a nephron. Filtration takes place in the structure labeled _____.
A) a
B) b
C) c
D) d



35) The osmoregulatory/excretory system of a freshwater flatworm is based on the operation of _____.
A) protonephridia
B) metanephridia
C) Malpighian tubules
D) nephrons





36) Materials are returned to the blood from the filtrate by which of the following processes?
A) filtration
B) selective reabsorption
C) secretion
D) excretion




37) Excretory organs known as Malpighian tubules are present in _____.
A) flatworms
B) insects
C) jellyfish
D) sea stars




38) The osmoregulatory process called secretion refers to the _____.
A) reabsorption of nutrients from a filtrate
B) selective elimination of excess ions and toxins from body fluids
C) formation of an osmotic gradient along an excretory structure
D) expulsion of urine from the body




39) The osmoregulatory/excretory system of an earthworm is based on the operation of _____.
A) protonephridia
B) metanephridia
C) Malpighian tubules
D) nephrons



40) Choose a pair that correctly associates the mechanism for osmoregulation or nitrogen removal with the appropriate animal.
A) metanephridium — flatworm
B) Malpighian tubule — frog
C) flame bulb — snake
D) exchange across the body surface — marine invertebrate





41) An excretory system that is partly based on the filtration of fluid under high hydrostatic pressure is the _____.
A) flame bulb system of flatworms
B) protonephridia of rotifers
C) Malpighian tubules of insects
D) kidneys of vertebrates




42) The transfer of fluid from the glomerulus to Bowman's capsule _____.
A) results from active transport
B) transfers large molecules as easily as small ones
C) is very selective as to which subprotein-sized molecules are transferred
D) is mainly a consequence of blood pressure in the capillaries of the glomerulus




43) Within a normally functioning kidney, blood can be found in _____.
A) the vasa recta
B) Bowman's capsule
C) the proximal tubule
D) the collecting duct




44) A primary reason that the kidneys have one of the highest metabolic rates of all body organs is that _____.
A) they have membranes of varying permeability to water
B) they operate an extensive set of active-transport ion pumps
C) they are the body's only means of shedding excess nutrients
D) they have an abundance of myogenic smooth muscle



45) Which process in the nephron is LEAST selective?
A) filtration
B) reabsorption
C) active transport
D) secretion





46) What is the function of the osmotic gradient found in the kidney? The osmotic gradient allows for _____.
A) electrolytes to move from low to high concentrations in the absence of ATP
B) the precise control of the retention of water and electrolytes
C) the loop of Henle to deliver water to the renal vein
D) the filtration of large cells at the glomerulus




47) The loop of Henle dips into the renal cortex. This is an important feature of osmoregulation in terrestrial vertebrates because _____.
A) absorptive processes taking place in the loop of Henle are hormonally regulated
B) differential permeabilities of ascending and descending limbs of the loop of Henle are important in establishing an osmotic gradient
C) the loop of Henle plays an important role in detoxification
D) additional filtration takes place along the loop of Henle




48) Low selectivity of solute movement is a characteristic of _____.
A) H+ pumping to control pH
B) reabsorption mechanisms along the proximal tubule
C) filtration from the glomerular capillaries
D) secretion along the distal tubule




49) If ATP production in a human kidney was suddenly halted, urine production would _____.
A) decrease, and the urine would be hypoosmotic compared to plasma
B) increase, and the urine would be isoosmotic compared to plasma
C) increase, and the urine would be hyperosmotic compared to plasma
D) decrease, and the urine would be isoosmotic compared to plasma

Bloom's Taxonomy:  Synthesis/Evaluation


50) Compared to wetland mammals, water conservation in mammals of arid regions is enhanced by having more _____.
A) juxtamedullary nephrons
B) urinary bladders
C) ureters
D) podocytes




51) Processing of filtrate in the proximal and distal tubules _____.
A) achieves the conversion of toxic ammonia to less toxic urea
B) maintains homeostasis of pH in body fluids
C) regulates the speed of blood flow through the nephrons
D) reabsorbs urea to maintain osmotic balance




52) In humans, the transport epithelial cells in the ascending loop of Henle _____.
A) are the largest epithelial cells in the body
B) are not in contact with interstitial fluid
C) have plasma membranes of low permeability to water
D) are not affected by high levels of nitrogenous wastes




53) The high osmolarity of the renal medulla is maintained by all of the following EXCEPT _____.
A) active transport of salt from the upper region of the ascending limb
B) the spatial arrangement of juxtamedullary nephrons
C) diffusion of urea from the collecting duct
D) diffusion of salt from the descending limb of the loop of Henle




54) Natural selection should favor the highest proportion of juxtamedullary nephrons in which of the following species?
A) a river otter
B) a mouse species living in a tropical rain forest
C) a mouse species living in a temperate broadleaf forest
D) a mouse species living in a desert



55) If you are hiking through the desert for several days, one would pack which of the following to ensure proper hydration?
A) a drink with a combination of water and electrolytes
B) caffeinated beverages
C) bottled water kept at room temperature
D) bottled water that had been frozen to ensure that it would be as cold as possible




56) Increased antidiuretic hormone (ADH) secretion is likely after _____.
A) drinking lots of pure water
B) sweating-induced dehydration increases plasma osmolarity
C) eating a small sugary snack
D) blood pressure becomes abnormally high




57) After blood flow is artificially reduced at one kidney, you would expect that kidney to secrete more of the hormone known as _____.
A) angiotensinogen
B) renin
C) antidiuretic hormone
D) atrial natriuretic peptide




58) After drinking alcoholic beverages, increased urine excretion is the result of _____.
A) increased aldosterone production
B) increased blood pressure
C) inhibited secretion of antidiuretic hormone (ADH)
D) increased reabsorption of water in the proximal tubule




59) Osmoregulatory adjustment via the renin-angiotensin-aldosterone system can be triggered by _____.
A) sleeping for one hour
B) severe sweating on a hot day
C) eating a pizza with olives and pepperoni
D) drinking several glasses of water



60) Antidiuretic hormone (ADH) and the renin-angiotensin-aldosterone system (the RAAS) work together in maintaining osmoregulatory homeostasis through which of the following ways?
A) ADH regulates the osmolarity of the blood by altering renal reabsorption of water, and the RAAS maintains the osmolarity of the blood by stimulating Na+ and water reabsorption.
B) ADH and the RAAS work antagonistically; ADH stimulates water reabsorption during dehydration and the RAAS causes increased excretion of water when it is in excess in body fluids.
C) Both stimulate the adrenal gland to secrete aldosterone, which increases both blood volume and pressure via its receptors in the urinary bladder.
D) ADH and the RAAS combine at the receptor sites of proximal tubule cells, where reabsorption of essential nutrients takes place.


 Campbell Biology, 10e (Reece)
Chapter 44   Osmoregulation and Excretion

1) The force driving simple diffusion is _____, while the energy source for active transport is _____.
A) the concentration gradient; ADP
B) the concentration gradient; ATP
C) transmembrane pumps; electron transport
D) phosphorylated protein carriers; ATP




2) To maintain homeostasis freshwater fish must _____.
A) excrete large quantities of electrolytes
B) consume large quantities of water
C) excrete large quantities of water
D) take in electrolytes through simple diffusion




3) Single-celled Paramecium live in pond water (a hypotonic environment). They have a structural feature, a contractile vacuole, which enables them to osmoregulate. If you observed them in the following solutions, at which sucrose concentration (in millimolars, mM) would you expect the contractile vacuole to be most active?
A) 0.0 mM sucrose
B) 0.05 mM saline
C) 0.08 mM sucrose
D) 1.0 mM saline




4) Sharks live in seawater. Their tissues are isotonic to seawater, but their concentrations of sodium ions, potassium ions, and chloride ions in cells and extracellular fluids are similar to those of freshwater fishes. How is that possible?
A) Urea and trimethylamine oxide contribute to intra- and extracellular osmolarity in shark tissues.
B) Metabolic intermediates of sharks tie up intracellular chloride and potassium ions.
C) Their blood is hypotonic to their tissues.
D) They excrete large quantities of electrolytes.




5) Hagfish (Eptatretus cirrhauts) are a jawless marine vertebrate that are isotonic with their environment and are considered to be osmoconformers. How might this interesting adaptation limit the habitat that the hagfish can tolerate?
A) Hagfish are not limited by salinity.
B) Osmoconformers do not face the same pressures as osmoregulators and can live in any marine environment.
C) Individual hagfish will adapt to different salinities over their lifetime and, therefore, can inhabit any marine environment.
D) Hagfish habitat is limited by the salinity of the environment.




6) Tissues of sharks are isotonic to seawater, but their concentrations of sodium ions, potassium ions, and chloride ions in cells and extracellular fluids are similar to those of freshwater fishes. What can you infer about the movement of sodium and chloride in these animals?
A) To maintain homeostasis of sodium and chloride levels, the shark must take up additional sodium and chloride from seawater.
B) Sodium and chloride will diffuse into shark gills from seawater down their concentration gradient.
C) Sharks conserve sodium and chloride, limiting excretion.
D) Sodium and chloride must be eliminated through the gills.




7) What role do chloride cells play in osmoregulation of marine fish with bony skeletons?
A) They actively transport chloride into the gills.
B) They mediate the movement of salt from seawater through their gills.
C) They are involved in excretion of excess salt.
D) They actively transport salt across the basolateral membrane of the rectal gland.




8) Salmon eggs hatch in freshwater. The fish then migrate to the ocean (a hypertonic solution) and, after several years of feeding and growing, return to freshwater to breed. How can these organisms make the transition from freshwater to ocean water and back to freshwater?
A) The rectal gland functions in the ocean water, and chloride cells function in freshwater.
B) Different gill cells are involved in osmoregulation in freshwater than in salt water.
C) Salmon in freshwater excrete dilute urine, and salmon in salt water secrete concentrated urine.
D) Their metabolism changes in salt water to degrade electrolytes.




9) Terrestrial organisms lose water through evaporation. In what ecosystem might an entomologist find a good study organism to examine the prevention of water loss?
A) wet rain forest
B) desert
C) prairie
D) chaparral




10) A necropsy (postmortem analysis) of a marine sea star that died after it was mistakenly placed in fresh water would likely show that it died because _____.
A) it was stressed and needed more time to acclimate to the new conditions
B) it was so hypertonic to the fresh water that it could not osmoregulate
C) its contractile vacuoles ruptured
D) its cells dehydrated and lost the ability to metabolize




11) The body fluids of an osmoconformer would be _____ with its _____ environment
A) isoosmotic; freshwater
B) hyperosmotic; saltwater
C) isoosmotic; saltwater
D) hypoosmotic; saltwater




12) Compared to the seawater around them, most marine invertebrates are _____.
A) hyperosmotic
B) hypoosmotic
C) isoosmotic
D) hyperosmotic and isoosmotic




13) The fluid with the highest osmolarity is _____.
A) distilled water
B) plasma in birds
C) plasma in mammals
D) seawater in a tidal pool




14) A human who has no access to fresh water but is forced to drink seawater instead will _____.
A) thrive under such conditions, as long as he has lived at the ocean most of his life
B) excrete more water molecules than taken in, because of the high load of ion ingestion
C) develop structural changes in the kidneys to accommodate the salt overload
D) risk becoming overhydrated within twelve hours




15) Unlike most bony fishes, sharks maintain body fluids that are isoosmotic to seawater, so they are considered by many to be osmoconformers. Nonetheless, these sharks osmoregulate at least partially by _____.
A) using their gills and kidneys to rid themselves of sea salts
B) monitoring dehydration at the cellular level with special gated aquaporins
C) tolerating high urea concentrations that are balanced with internal salt concentrations to seawater osmolarity
D) synthesizing trimethylamine oxide, a chemical that binds and precipitates salts inside cells




16) The necropsy (postmortem analysis) of a freshwater fish that died after being placed accidentally in saltwater would likely show that _____.
A) loss of water by osmosis from cells in vital organs resulted in cell death and organ failure
B) high amounts of salt had diffused into the fish's cells, causing them to swell and lyse
C) the kidneys were not able to keep up with the water removal necessary in this hyperosmotic environment, creating an irrevocable loss of homeostasis
D) the gills became encrusted with salt, resulting in inadequate gas exchange and a resulting asphyxiation




17) Which of the following animals generally has the lowest volume of urine production?
A) a vampire bat
B) a salmon in fresh water
C) a marine bony fish
D) a shark inhabiting the Mississippi River




18) One of the waste products that accumulates during cellular functions is carbon dioxide. It is removed via the respiratory system. What is another waste product that accumulates during normal physiological functions in vertebrates?
I)   ammonia
II)  uric acid
III)      urea
A) only I and III
B) only II and III
C) only I and II
D) I, II, and III




19) Urea is produced in the _____.
A) liver from NH3 and carbon dioxide
B) liver from glycogen
C) kidneys from glycerol and fatty acids
D) bladder from uric acid and water




20) Urea is _____.
A) insoluble in water
B) the primary nitrogenous waste product of humans
C) the primary nitrogenous waste product of most birds
D) the primary nitrogenous waste product of most aquatic invertebrates




21) Which nitrogenous waste has the greatest number of nitrogen atoms?
A) ammonia
B) ammonium ions
C) urea
D) uric acid





22) Ammonia is likely to be the primary nitrogenous waste in living conditions that include _____.
A) lots of fresh water flowing across the gills of a fish
B) lots of seawater, such as a bird living in a marine environment
C) a terrestrial environment, such as that supporting crickets
D) a moist system of burrows, such as those of naked mole rats



23) Excessive formation of uric acid crystals in humans leads to _____.
A) a condition called diabetes, where excessive urine formation occurs
B) a condition of insatiable thirst and excessive urine formation
C) gout, a painful inflammatory disease that primarily affects the joints
D) osteoarthritis, an inevitable consequence of aging




24) Ammonia _____.
A) is soluble in water
B) has low toxicity relative to urea
C) is metabolically more expensive to synthesize than urea
D) is the major nitrogenous waste excreted by insects




25) The advantage of excreting nitrogenous wastes as urea rather than as ammonia is that _____.
A) urea can be exchanged for Na+
B) urea is less toxic than ammonia
C) urea does not affect the osmolar gradient
D) less nitrogen is removed from the body




26) In animals, nitrogenous wastes are produced mostly from the catabolism of _____.
A) starch and cellulose
B) triglycerides and steroids
C) proteins and nucleic acids
D) phospholipids and glycolipids





27) Birds secrete uric acid as their nitrogenous waste because uric acid _____.
A) is readily soluble in water
B) is metabolically less expensive to synthesize than other excretory products
C) requires little water for nitrogenous waste disposal, thus reducing body mass
D) can be reused by birds as a protein source



28) Among the following choices, the most concentrated urine is excreted by _____.
A) frogs
B) kangaroo rats
C) humans
D) freshwater bass




29) African lungfish, which are often found in small, stagnant pools of fresh water, produce urea as a nitrogenous waste. What is the advantage of this adaptation?
A) Urea takes less energy to synthesize than ammonia.
B) Small, stagnant pools do not provide enough water to dilute the toxic ammonia.
C) The highly toxic urea makes the pool uninhabitable to potential competitors.
D) Urea makes lungfish tissue hypoosmotic to the pool.




30) Which of the following most accurately describes selective permeability?
A) An input of energy is required for transport.
B) Lipid-soluble molecules pass through a membrane.
C) There must be a concentration gradient for molecules to pass through a membrane.
D) Only certain molecules can cross a cell membrane.





31) Through studies of insect Malpighian tubules, researchers found that K+ accumulated on the inner face of the tubule, against its concentration gradient. What can you infer about the mechanism of transport?
A) Potassium transport is a passive process.
B) Movement of potassium into the lumen of the Malpighian tubules is an energy-requiring process.
C) Potassium moves out of the tubules at a faster rate than it moves into the lumen of the tubules.
D) Sodium ions will follow potassium ions.




32) A potassium ion gradient is set up in insect Malpighian tubules through an active transport process. As a result, potassium concentration is higher in the lumen of the tubules than in hemolymph. How would the potassium gradient affect water movement?
A) Water would be forced out of the lumen of the Malpighian tubules through an osmotic gradient.
B) The potassium gradient would have no effect on water movement.
C) There would be a net movement of water into the lumen of the tubules.
D) Water would be conserved, forming a hypertonic solution in the Malpighian tubules.



33) Why are the renal artery and vein critical to the process of osmoregulation in vertebrates?
A) The kidneys require constant and abnormally high oxygen supply to function.
B) The renal artery delivers blood with nitrogenous waste to the kidney and the renal vein brings blood with less nitrogenous wastes away from the kidneys.
C) The kidneys require higher than normal levels of hormones.
D) The renal artery and vein are the main pathways regulating how much is produced by the kidneys.




34) The figure above shows a nephron. Filtration takes place in the structure labeled _____.
A) a
B) b
C) c
D) d



35) The osmoregulatory/excretory system of a freshwater flatworm is based on the operation of _____.
A) protonephridia
B) metanephridia
C) Malpighian tubules
D) nephrons





36) Materials are returned to the blood from the filtrate by which of the following processes?
A) filtration
B) selective reabsorption
C) secretion
D) excretion




37) Excretory organs known as Malpighian tubules are present in _____.
A) flatworms
B) insects
C) jellyfish
D) sea stars




38) The osmoregulatory process called secretion refers to the _____.
A) reabsorption of nutrients from a filtrate
B) selective elimination of excess ions and toxins from body fluids
C) formation of an osmotic gradient along an excretory structure
D) expulsion of urine from the body




39) The osmoregulatory/excretory system of an earthworm is based on the operation of _____.
A) protonephridia
B) metanephridia
C) Malpighian tubules
D) nephrons



40) Choose a pair that correctly associates the mechanism for osmoregulation or nitrogen removal with the appropriate animal.
A) metanephridium — flatworm
B) Malpighian tubule — frog
C) flame bulb — snake
D) exchange across the body surface — marine invertebrate





41) An excretory system that is partly based on the filtration of fluid under high hydrostatic pressure is the _____.
A) flame bulb system of flatworms
B) protonephridia of rotifers
C) Malpighian tubules of insects
D) kidneys of vertebrates




42) The transfer of fluid from the glomerulus to Bowman's capsule _____.
A) results from active transport
B) transfers large molecules as easily as small ones
C) is very selective as to which subprotein-sized molecules are transferred
D) is mainly a consequence of blood pressure in the capillaries of the glomerulus




43) Within a normally functioning kidney, blood can be found in _____.
A) the vasa recta
B) Bowman's capsule
C) the proximal tubule
D) the collecting duct




44) A primary reason that the kidneys have one of the highest metabolic rates of all body organs is that _____.
A) they have membranes of varying permeability to water
B) they operate an extensive set of active-transport ion pumps
C) they are the body's only means of shedding excess nutrients
D) they have an abundance of myogenic smooth muscle



45) Which process in the nephron is LEAST selective?
A) filtration
B) reabsorption
C) active transport
D) secretion





46) What is the function of the osmotic gradient found in the kidney? The osmotic gradient allows for _____.
A) electrolytes to move from low to high concentrations in the absence of ATP
B) the precise control of the retention of water and electrolytes
C) the loop of Henle to deliver water to the renal vein
D) the filtration of large cells at the glomerulus




47) The loop of Henle dips into the renal cortex. This is an important feature of osmoregulation in terrestrial vertebrates because _____.
A) absorptive processes taking place in the loop of Henle are hormonally regulated
B) differential permeabilities of ascending and descending limbs of the loop of Henle are important in establishing an osmotic gradient
C) the loop of Henle plays an important role in detoxification
D) additional filtration takes place along the loop of Henle




48) Low selectivity of solute movement is a characteristic of _____.
A) H+ pumping to control pH
B) reabsorption mechanisms along the proximal tubule
C) filtration from the glomerular capillaries
D) secretion along the distal tubule




49) If ATP production in a human kidney was suddenly halted, urine production would _____.
A) decrease, and the urine would be hypoosmotic compared to plasma
B) increase, and the urine would be isoosmotic compared to plasma
C) increase, and the urine would be hyperosmotic compared to plasma
D) decrease, and the urine would be isoosmotic compared to plasma

Bloom's Taxonomy:  Synthesis/Evaluation


50) Compared to wetland mammals, water conservation in mammals of arid regions is enhanced by having more _____.
A) juxtamedullary nephrons
B) urinary bladders
C) ureters
D) podocytes




51) Processing of filtrate in the proximal and distal tubules _____.
A) achieves the conversion of toxic ammonia to less toxic urea
B) maintains homeostasis of pH in body fluids
C) regulates the speed of blood flow through the nephrons
D) reabsorbs urea to maintain osmotic balance




52) In humans, the transport epithelial cells in the ascending loop of Henle _____.
A) are the largest epithelial cells in the body
B) are not in contact with interstitial fluid
C) have plasma membranes of low permeability to water
D) are not affected by high levels of nitrogenous wastes




53) The high osmolarity of the renal medulla is maintained by all of the following EXCEPT _____.
A) active transport of salt from the upper region of the ascending limb
B) the spatial arrangement of juxtamedullary nephrons
C) diffusion of urea from the collecting duct
D) diffusion of salt from the descending limb of the loop of Henle




54) Natural selection should favor the highest proportion of juxtamedullary nephrons in which of the following species?
A) a river otter
B) a mouse species living in a tropical rain forest
C) a mouse species living in a temperate broadleaf forest
D) a mouse species living in a desert



55) If you are hiking through the desert for several days, one would pack which of the following to ensure proper hydration?
A) a drink with a combination of water and electrolytes
B) caffeinated beverages
C) bottled water kept at room temperature
D) bottled water that had been frozen to ensure that it would be as cold as possible




56) Increased antidiuretic hormone (ADH) secretion is likely after _____.
A) drinking lots of pure water
B) sweating-induced dehydration increases plasma osmolarity
C) eating a small sugary snack
D) blood pressure becomes abnormally high




57) After blood flow is artificially reduced at one kidney, you would expect that kidney to secrete more of the hormone known as _____.
A) angiotensinogen
B) renin
C) antidiuretic hormone
D) atrial natriuretic peptide




58) After drinking alcoholic beverages, increased urine excretion is the result of _____.
A) increased aldosterone production
B) increased blood pressure
C) inhibited secretion of antidiuretic hormone (ADH)
D) increased reabsorption of water in the proximal tubule




59) Osmoregulatory adjustment via the renin-angiotensin-aldosterone system can be triggered by _____.
A) sleeping for one hour
B) severe sweating on a hot day
C) eating a pizza with olives and pepperoni
D) drinking several glasses of water



60) Antidiuretic hormone (ADH) and the renin-angiotensin-aldosterone system (the RAAS) work together in maintaining osmoregulatory homeostasis through which of the following ways?
A) ADH regulates the osmolarity of the blood by altering renal reabsorption of water, and the RAAS maintains the osmolarity of the blood by stimulating Na+ and water reabsorption.
B) ADH and the RAAS work antagonistically; ADH stimulates water reabsorption during dehydration and the RAAS causes increased excretion of water when it is in excess in body fluids.
C) Both stimulate the adrenal gland to secrete aldosterone, which increases both blood volume and pressure via its receptors in the urinary bladder.
D) ADH and the RAAS combine at the receptor sites of proximal tubule cells, where reabsorption of essential nutrients takes place.



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